Fam120c MGI Mouse Gene Detail - MGI:2387687 - family with sequence similarity 120, member C

Symbol

Fam120c
Name

family with sequence similarity 120, member C
Synonyms

D930001I21Rik, orf34

Feature Type

protein coding gene
IDs

MGI:2387687
NCBI Gene: 207375
Alliance

gene page
Transcription Start Sites

4 TSS

Sequence Map

ChrX:150127171-150254838 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome X, 68.46 cM, cytoband F2
Mapping Data

2 experiments

SNPs within 2kb

460 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2387687	protein coding gene	ChrX:150125515-150257135 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0036177	protein coding gene	ChrX:149098641-149223413 (+)
A/J	MGP_AJ_G0036153	protein coding gene	ChrX:148289289-148428902 (+)
AKR/J	MGP_AKRJ_G0036079	protein coding gene	ChrX:153080241-153218135 (+)
BALB/cJ	MGP_BALBcJ_G0036144	protein coding gene	ChrX:146488393-146615324 (+)
C3H/HeJ	MGP_C3HHeJ_G0035852	protein coding gene	ChrX:149293393-149418103 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0036669	protein coding gene	ChrX:153324274-153452604 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0033493	protein coding gene	ChrX:140025359-140144016 (+)
CAST/EiJ	MGP_CASTEiJ_G0035143	protein coding gene	ChrX:128728799-128854796 (+)
CBA/J	MGP_CBAJ_G0035829	protein coding gene	ChrX:157853521-157990469 (+)
DBA/2J	MGP_DBA2J_G0035987	protein coding gene	ChrX:147384460-147507758 (+)
FVB/NJ	MGP_FVBNJ_G0035921	protein coding gene	ChrX:146512942-146643241 (+)
LP/J	MGP_LPJ_G0036078	protein coding gene	ChrX:150163610-150292073 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0035957	protein coding gene	ChrX:165974267-166129971 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0036704	protein coding gene	ChrX:148584101-148714661 (+)
PWK/PhJ	MGP_PWKPhJ_G0034837	protein coding gene	ChrX:125704121-125828805 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0034663	protein coding gene	ChrX:129191118-129314831 (+)
WSB/EiJ	MGP_WSBEiJ_G0035278	protein coding gene	ChrX:146686325-146812940 (+)

Human Ortholog

FAM120C, family with sequence similarity 120 member C

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

FAM120C, family with sequence similarity 120 member C
Synonyms

CXorf17, ORF34
Links

HGNC:16949

NCBI Gene ID: 54954

neXtProt AC: NX_Q9NX05

UniProt: Q9NX05
Chr Location

Xp11.22; chrX:54068324-54183281 (-) GRCh38

MGI Vertebrate Homology

Fam120c stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: FAM120C
Gene Tree

Fam120c

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Phenotype Summary

10 phenotypes from 2 alleles in 2 genetic backgrounds
9 images
7 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

9
Endonuclease-mediated

3
Gene trapped

4
Targeted

2
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

15 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

Male chimeras hemizygous for a gene trapped allele appear phenotypically normal at E9.5.

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All GO Annotations

1
GO References

1

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

719
Tissues

12
cDNA Data

9
Literature Summary

1

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase fam120c

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All Sequences

44
RefSeq

7
UniProt

3
CCDS

CCDS41175.1

Ensembl

ENSMUSG00000025262 (Evidence)
NCBI Gene

207375

			Length	Strain/Species	Flank
genomic	ENSMUSG00000025262	Ensembl Gene Model \| MGI Sequence Detail	127668	C57BL/6J	± kb
transcript	ENSMUST00000073364	Ensembl \| MGI Sequence Detail	5463	Not Applicable
polypeptide	ENSMUSP00000073082	Ensembl \| MGI Sequence Detail	1091	Not Applicable

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UniProt

3 Sequences
Protein Ontology

PR:000030920 constitutive coactivator of PPAR-gamma-like protein 2

(term hierarchy)
InterPro Domains

IPR026784 Constitutive coactivator of PPAR-gamma

IPR029060 PIN-like domain superfamily

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All nucleic 10

cDNA 9

Primer pair 1

Microarray probesets 3

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MGI:2443307

Summaries

All 27

Developmental Gene Expression 1

Gene Ontology 1

Phenotypes 7
Earliest

J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
Latest

J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

TSS for Fam120c:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr162338	ChrX:150126858-150126902 (+)	-291 bp
Tssr162339	ChrX:150127167-150127193 (+)	9 bp
Tssr162340	ChrX:150127203-150127236 (+)	49 bp
Tssr162341	ChrX:150142334-150142338 (+)	15,165 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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