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Sema6d
Gene Detail
Symbol

Name
ID
Sema6d
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
MGI:2387661
Synonyms
1110067B02Rik, mKIAA1479, Sema6D-1, Sema6D-2, Sema6D-4, Sema6D-5, Sema6D-6
Feature Type
protein coding gene
Genetic Map
Chromosome 2
60.69 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr2:124089969-124667770 bp, + strand
From VEGA annotation of GRCm38

  577802 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:16195  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: semaphorin
Gene Tree: Sema6d

Human
homologs
Human Homolog SEMA6D, sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
NCBI Gene ID 80031
neXtProt AC  NX_Q8NFY4
Human Chr (Location)  15q21.1; chr15:47184206-47774223 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(4) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit normal dendritic cell trafficking and antigen-specific T cell priming.
 
Interactions
Sema6d interacts with 353 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process cell differentiation, multicellular organismal development, ...
Component integral component of membrane, membrane, ...
Function protein binding, receptor activity, ...
External Resources: FuncBase
Expression
Literature Summary: (13 records)
Data Summary: Results (319)    Tissues (91)    Images (48)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 319
cDNA source data(12)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(14) cDNA(13) Other(1)
Microarray probesets(7)
Other database
links
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015256 VEGA Gene Model | MGI Sequence Detail 577802 C57BL/6J ±  kb
transcript OTTMUST00000036150 VEGA | MGI Sequence Detail 6225 Not Applicable 
polypeptide OTTMUSP00000016242 VEGA | MGI Sequence Detail 1073 Not Applicable 

For the selected sequences
All sequences(110) RefSeq(34) UniProt(3)
Polymorphisms
SNPs within 2kb(2647 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002165 Plexin
InterPro IPR016201 Plexin-like fold
InterPro IPR027231 Semaphorin
InterPro IPR001627 Semaphorin/CD100 antigen
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000014632 semaphorin-6D
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:202884 Sun LO, et al., On and off retinal circuit assembly by divergent molecular mechanisms. Science. 2013 Nov 1;342(6158):1241974
All references(47)
Other
accession IDs
MGI:1916098, MGI:2138763

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory