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Sema6d Gene Detail
Summary
  • Symbol
    Sema6d
  • Name
    sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
  • Synonyms
    1110067B02Rik, mKIAA1479, Sema6D-1, Sema6D-2, Sema6D-4, Sema6D-5, Sema6D-6
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387661
    NCBI Gene: 214968
Location & Maps
more
  • Sequence Map
    Chr2:124089969-124667770 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      577802 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 60.69 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    SEMA6D, semaphorin 6D
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SEMA6D, semaphorin 6D
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 80031
    neXtProt AC: NX_Q8NFY4

  • Chr Location
    15q21.1; chr15:47184101-47774223 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    14 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    1
  • Gene trapped
    4
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Sema6d
  • Incidental Mutations
Mice homozygous for a knock-out allele exhibit normal dendritic cell trafficking and antigen-specific T cell priming.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015256 VEGA Gene Model | MGI Sequence Detail 577802 C57BL/6J ±  kb
transcript OTTMUST00000036150 VEGA | MGI Sequence Detail 6225 Not Applicable  
polypeptide OTTMUSP00000016242 VEGA | MGI Sequence Detail 1073 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    2644 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 13
    Other 1

    Microarray probesets 7
Other
Accession IDs
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MGI:1916098, MGI:2138763
References
more
  • Summaries
    All 48
    Developmental Gene Expression 16
    Gene Ontology 5
    Phenotypes 14
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:229438 Andrews WD, et al., Altered proliferative ability of neuronal progenitors in PlexinA1 mutant mice. J Comp Neurol. 2016 Feb 15;524(3):518-34

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory