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Sema6d
Gene Detail
 Symbol
Name
ID
Sema6d
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
MGI:2387661
Synonyms 1110067B02Rik, mKIAA1479, Sema6D-1, Sema6D-2, Sema6D-4, Sema6D-5, Sema6D-6
Feature Type protein coding gene
Genetic Map
Chromosome 2
60.69 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr2:124089969-124667770 bp, + strand
From VEGA annotation of GRCm38

  577802 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:16195  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: semaphorin
Gene Tree: Sema6d

Human
homologs
Human Homolog SEMA6D, sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
NCBI Gene ID 80031
neXtProt AC  NX_Q8NFY4
Human Chr (Location)  15q21.1; chr15:47184206-47774223 (+)  GRCh38
Alleles
and
phenotypes
All alleles(7) : Targeted(3) Gene trapped(4)
 
Mice homozygous for a knock-out allele exhibit normal dendritic cell trafficking and antigen-specific T cell priming.
 
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process cell differentiation, multicellular organismal development, ...
Component integral component of membrane, membrane, ...
Function protein binding, receptor activity, ...
External Resources: FuncBase
Expression
Literature Summary: (13 records)
Data Summary: Results (319)    Tissues (91)    Images (48)
Theiler Stages: 19, 20, 21, 22, 23, 24, 28
Assay TypeResults
RNA in situ 319
cDNA source data(12)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress
Molecular
reagents
All nucleic(14) cDNA(13) Other(1)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000015256 (Evidence)
Ensembl Gene ModelENSMUSG00000027200 (Evidence)
Entrez Gene214968 (Evidence)
DFCITC1578641, TC1588584, TC1594841, TC1601288, TC1601351, TC1602887, TC1604456, TC1664620, TC1712394
DoTSDT.101394682, DT.101736718, DT.103567239, DT.103567243, DT.110692721, DT.522834, DT.91318249, DT.91378815
NIA Mouse Gene IndexU002402
Consensus CDS ProjectCCDS16670.1, CCDS16671.1, CCDS16672.1, CCDS16673.1, CCDS38225.1
International Mouse Knockout Project StatusSema6d
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015256 VEGA Gene Model | MGI Sequence Detail 577802 C57BL/6J ±  kb
transcript OTTMUST00000036150 VEGA | MGI Sequence Detail 6225 Not Applicable 
polypeptide OTTMUSP00000016242 VEGA | MGI Sequence Detail 1073 Not Applicable 

For the selected sequences
All sequences(110) RefSeq(34) UniProt(3)
Polymorphisms SNPs within 2kb(2647 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002165 Plexin
InterPro IPR016201 Plexin-like fold
InterPro IPR027231 Semaphorin
InterPro IPR001627 Semaphorin/CD100 antigen
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000014632 semaphorin-6D
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:202884 Sun LO, et al., On and off retinal circuit assembly by divergent molecular mechanisms. Science. 2013 Nov 1;342(6158):1241974
All references(47)
Other
accession IDs
MGI:1916098, MGI:2138763

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory