About   Help   FAQ
Cxcl17 Gene Detail
Summary
  • Symbol
    Cxcl17
  • Name
    chemokine (C-X-C motif) ligand 17
  • Synonyms
    MGC:37641
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387642
    NCBI Gene: 232983
  • Alliance
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:25400053-25412886 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 13.80 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    132 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2387642
protein coding gene Chr7:25400053-25412886 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031866
protein coding gene Chr7:23870529-23885174 (-)
A/J MGP_AJ_G0031845
protein coding gene Chr7:23248202-23261033 (-)
AKR/J MGP_AKRJ_G0031774
protein coding gene Chr7:23795530-23810561 (-)
BALB/cJ MGP_BALBcJ_G0031852
protein coding gene Chr7:23461993-23475285 (-)
C3H/HeJ MGP_C3HHeJ_G0031571
protein coding gene Chr7:24230916-24244313 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032314
protein coding gene Chr7:24668871-24687331 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029369
protein coding gene Chr7:24669832-24680178 (-)
CAST/EiJ MGP_CASTEiJ_G0030911
protein coding gene Chr7:17718804-17732721 (-)
CBA/J MGP_CBAJ_G0031536
protein coding gene Chr7:25579950-25597607 (-)
DBA/2J MGP_DBA2J_G0031690
protein coding gene Chr7:23150320-23162879 (-)
FVB/NJ MGP_FVBNJ_G0031643
protein coding gene Chr7:23152783-23165571 (-)
LP/J MGP_LPJ_G0031769
protein coding gene Chr7:24166814-24181442 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031680
protein coding gene Chr7:25280158-25295334 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032346
protein coding gene Chr7:23501352-23515701 (-)
PWK/PhJ MGP_PWKPhJ_G0030635
protein coding gene Chr7:18097882-18110371 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030466
protein coding gene Chr7:14822601-14834371 (-)
WSB/EiJ MGP_WSBEiJ_G0031014
protein coding gene Chr7:23687475-23701176 (-)



Homology
more
  • Human Ortholog
    CXCL17, C-X-C motif chemokine ligand 17
  • Vertebrate Orthologs
    6
  • Human Ortholog
    CXCL17, C-X-C motif chemokine ligand 17
    Orthology source: HomoloGene, HGNC
  • Synonyms
    Dcip1, DMC, UNQ473, VCC1, VCC-1
  • Links
    NCBI Gene ID: 284340
    neXtProt AC: NX_Q6UXB2
    UniProt: Q6UXB2

  • Chr Location
    19q13.2; chr19:42428538-42443048 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 232983 NCBI Gene Model | MGI Sequence Detail 12834 C57BL/6J ±  kb
transcript NM_153576 RefSeq | MGI Sequence Detail 760 Not Specified  
polypeptide Q5UW37 UniProt | EBI | MGI Sequence Detail 119 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 4
References
more
  • Summaries
    All 35
    Gene Ontology 5
    Phenotypes 13
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:260951 Srivastava R, et al., CXCL17 Chemokine-Dependent Mobilization of CXCR8(+)CD8(+) Effector Memory and Tissue-Resident Memory T Cells in the Vaginal Mucosa Is Associated with Protection against Genital Herpes. J Immunol. 2018 Apr 15;200(8):2915-2926

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2019
MGI 6.14
The Jackson Laboratory