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Fkbp14
Gene Detail
Symbol

Name
ID
Fkbp14
FK506 binding protein 14
MGI:2387639
Synonyms
FKBP22, MGC:18737
Feature Type
protein coding gene
Genetic Map
Chromosome 6
27.01 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr6:54577604-54597344 bp, - strand
From VEGA annotation of GRCm38

  19741 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23059  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: FKBP14
Gene Tree: Fkbp14

Human
homologs
FKBP14, FK506 binding protein 14, 22 kDa
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 55033
neXtProt AC: NX_Q9NWM8

Human Synonyms: EDSKMH, FKBP22, IPBP12

Human Chr (Location): 7p14.3; chr7:30010583-30026801 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human FKBP14

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from CvDC )
Interactions
Fkbp14 interacts with 268 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process chaperone-mediated protein folding, protein folding, ...
Component cytoplasm, endoplasmic reticulum, ...
Function calcium ion binding, FK506 binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (10)    Images (23)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(7)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase fkbp14 ; ZFIN fkbp14    NEW 
Molecular
reagents
All nucleic(7) cDNA(7)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000026988 (Evidence)
Ensembl Gene Model ENSMUSG00000038074 (Evidence)
Entrez Gene 231997 (Evidence)
DFCI TC1575615, TC1606151, TC1606334
DoTS DT.101272694, DT.101288567, DT.101343048, DT.101389754, DT.488430
NIA Mouse Gene Index U027338
EC 5.2.1.8
Consensus CDS Project CCDS20157.1
International Mouse Phenotyping Consortium Status Fkbp14
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026988 VEGA Gene Model | MGI Sequence Detail 19741 C57BL/6J ±  kb
transcript OTTMUST00000066698 VEGA | MGI Sequence Detail 2694 Not Applicable 
polypeptide OTTMUSP00000033469 VEGA | MGI Sequence Detail 211 Not Applicable 

For the selected sequences
All sequences(52) RefSeq(3) UniProt(6)
Polymorphisms
SNPs within 2kb(54 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR018247 EF-Hand 1, calcium-binding site
InterPro IPR002048 EF-hand domain
InterPro IPR011992 EF-hand-like domain
InterPro IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type
InterPro IPR001179 Peptidyl-prolyl cis-trans isomerase, FKBP-type, domain
Protein Ontology PR:000007534 peptidyl-prolyl cis-trans isomerase FKBP14
References
(Earliest) J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory