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Fkbp14 Gene Detail
Summary
  • Symbol
    Fkbp14
  • Name
    FK506 binding protein 14
  • Synonyms
    FKBP22, MGC:18737
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387639
    NCBI Gene: 231997
Location & Maps
more
  • Sequence Map
    Chr6:54577604-54597308 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      19705 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    FKBP14, FK506 binding protein 14
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FKBP14, FK506 binding protein 14
    Orthology source: HGNC, HomoloGene
  • Synonyms
    EDSKMH, FKBP22, IPBP12
  • Links
    NCBI Gene ID: 55033
    neXtProt AC: NX_Q9NWM8

  • Chr Location
    7p14.3; chr7:30010583-30026801 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human FKBP14 associations

Human Disease Mouse Models
       Ehlers-Danlos Syndrome with Progressive Kyphoscoliosis, Myopathy, and Hearing Loss; EDSKMH   OMIM: 614557
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotype references
  • All Mutations and Alleles
    2
  • Targeted
    2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026988 VEGA Gene Model | MGI Sequence Detail 19705 C57BL/6J ±  kb
transcript OTTMUST00000066698 VEGA | MGI Sequence Detail 2694 Not Applicable  
polypeptide OTTMUSP00000033469 VEGA | MGI Sequence Detail 211 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    53 from dbSNP Build 142
Protein
Information
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  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000007534 peptidyl-prolyl cis-trans isomerase FKBP14
  • EC
  • InterPro Domains
    IPR018247 EF-Hand 1, calcium-binding site
    IPR002048 EF-hand domain
    IPR011992 EF-hand domain pair
    IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain
    IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type
Molecular
Reagents
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  • All nucleic 7
    cDNA 7

    Microarray probesets 3
References
more
  • Summaries
    All 24
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory