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Lrrc66 Gene Detail
Summary
  • Symbol
    Lrrc66
  • Name
    leucine rich repeat containing 66
  • Synonyms
    MGC:38937
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387634
    NCBI Gene: 231296
Location & Maps
more
  • Sequence Map
    Chr5:73606642-73632526 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      25885 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    LRRC66, leucine rich repeat containing 66
  • Vertebrate Orthologs
    7
  • Human Ortholog
    LRRC66, leucine rich repeat containing 66
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 339977
    neXtProt AC: NX_Q68CR7

  • Chr Location
    4q12; chr4:51993640-52020311 (-)  GRCh38.p2

Human Diseases
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  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    227 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    2
  • Radiation induced
    1
  • Spontaneous
    3
  • Targeted
    2
  • Genomic Mutations
    6 involving Lrrc66
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026766 VEGA Gene Model | MGI Sequence Detail 25885 C57BL/6J ±  kb
transcript OTTMUST00000066196 VEGA | MGI Sequence Detail 3198 Not Applicable  
polypeptide OTTMUSP00000033133 VEGA | MGI Sequence Detail 872 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    397 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000032741 leucine-rich repeat-containing protein 66
  • InterPro Domains
    IPR001611 Leucine-rich repeat
    IPR032675 Leucine-rich repeat domain, L domain-like
    IPR003591 Leucine-rich repeat, typical subtype
Molecular
Reagents
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  • All nucleic 6
    cDNA 6

    Microarray probesets 2
References
more
  • Summaries
    All 20
    Diseases 1
    Gene Ontology 2
    Phenotypes 227
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory