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Ahsa1 Gene Detail
Summary
  • Symbol
    Ahsa1
  • Name
    AHA1, activator of heat shock protein ATPase 1
  • Synonyms
    Aha1, MGC:36589, MGC:36618, p38
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387603
    NCBI Gene: 217737
  • Gene Overview
    MyGene.info: AHSA1
Location & Maps
more
  • Sequence Map
    Chr12:87266746-87273997 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7252 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 41.47 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    AHSA1, activator of Hsp90 ATPase activity 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    AHSA1, activator of Hsp90 ATPase activity 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    AHA1, C14orf3, hAha1, p38
  • Links
    NCBI Gene ID: 10598
    neXtProt AC: NX_O95433

  • Chr Location
    14q24; chr14:77457875-77469472 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 8106
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: AHSA1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    21
  • Chemically induced (other)
    1
  • Gene trapped
    17
  • Targeted
    3
  • Genomic Mutations
    1 involving Ahsa1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021037 Ensembl Gene Model | MGI Sequence Detail 7252 C57BL/6J ±  kb
transcript ENSMUST00000021425 Ensembl | MGI Sequence Detail 1347 Not Applicable  
polypeptide ENSMUSP00000021425 Ensembl | MGI Sequence Detail 338 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    57 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000003860 activator of 90 kDa heat shock protein ATPase homolog 1
  • InterPro Domains
    IPR013538 Activator of Hsp90 ATPase homologue 1-like
    IPR015310 Activator of Hsp90 ATPase, N-terminal
    IPR023393 START-like domain
Molecular
Reagents
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  • All nucleic 190
    cDNA 190

    Microarray probesets 2
References
more
  • Summaries
    All 29
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
  • Latest
    J:201478 Desjardins F, et al., Modulation of the cochaperone AHA1 regulates heat-shock protein 90 and endothelial NO synthase activation by vascular endothelial growth factor. Arterioscler Thromb Vasc Biol. 2012 Oct;32(10):2484-92

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory