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Gabrp
Gene Detail
 Symbol
Name
ID
Gabrp
gamma-aminobutyric acid (GABA) A receptor, pi
MGI:2387597
Feature Type protein coding gene
Genetic Map
Chromosome 11
19.21 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:33550781-33578959 bp, - strand
From VEGA annotation of GRCm38

  28179 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22798  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Gabrp

Human
homologs
Human Homolog GABRP, gamma-aminobutyric acid (GABA) A receptor, pi
NCBI Gene ID 2568
neXtProt AC  NX_O00591
Human Chr (Location)  5q35.1; chr5:170783719-170814047 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(3) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene does not appear to result in a phenotype.
 
Interactions
Gabrp interacts with 192 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process chloride transport, ion transport, ...
Component cell junction, chloride channel complex, ...
Function chloride channel activity, extracellular ligand-gated ion channel activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (78)    Tissues (56)    Images (17)
Theiler Stages: 28
Assay TypeResults
In situ reporter (knock in) 40
RT-PCR 38
cDNA source data(27)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(28) cDNA(27) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000006342 (Evidence)
Ensembl Gene ModelENSMUSG00000020159 (Evidence)
Entrez Gene216643 (Evidence)
UniGene99989
DFCITC1580863
DoTSDT.55214000, DT.60103382
NIA Mouse Gene IndexU032644
Consensus CDS ProjectCCDS24535.1
International Mouse Knockout Project StatusGabrp
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006342 VEGA Gene Model | MGI Sequence Detail 28179 C57BL/6J ±  kb
transcript OTTMUST00000014419 VEGA | MGI Sequence Detail 3280 Not Applicable 
polypeptide OTTMUSP00000006688 VEGA | MGI Sequence Detail 440 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(4) UniProt(3)
Polymorphisms SNPs within 2kb(98 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006028 Gamma-aminobutyric acid A receptor
InterPro IPR008100 Gamma-aminobutyric-acid A receptor pi subunit
InterPro IPR006201 Neurotransmitter-gated ion-channel
InterPro IPR018000 Neurotransmitter-gated ion-channel, conserved site
InterPro IPR006202 Neurotransmitter-gated ion-channel ligand-binding
InterPro IPR006029 Neurotransmitter-gated ion-channel transmembrane domain
Protein Ontology PR:000007780 gamma-aminobutyric acid receptor subunit pi
References (Earliest) J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
(Latest) J:185665 Guo Z, et al., Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20
All references(32)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory