Gabrp
Gene Detail

Symbol Name ID

Gabrp gamma-aminobutyric acid (GABA) A receptor, pi MGI:2387597

Feature Type

protein coding gene

Genetic Map

Chromosome 11

19.21 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr11:33550781-33578959 bp, - strand From VEGA annotation of GRCm38   28179 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Mammalian homology

human; rat; cattle; chimpanzee; dog, domestic    (Mammalian Orthology)
Comparative Map (Mouse/Human Gabrp ± 2 cM)

Gene Tree: Gabrp

Human ortholog

GABRP gamma-aminobutyric acid (GABA) A receptor, pi NCBI Gene ID 2568
Human Chr5:170210723-170241051 bp, + strand Reference GRCh37.p2 Primary Assembly

Alleles and phenotypes

All alleles(6) : Targeted(3) Gene trapped(3)
 

Homozygous mutation of this gene does not appear to result in a phenotype.

 

Gene Ontology (GO) classifications

All GO classifications: (19 annotations)

Process	chloride transport, ion transport, ...
Component	cell junction, chloride channel complex, ...
Function	chloride channel activity, extracellular ligand-gated ion channel activity, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (78)    Tissues (56)    Images (17)
Theiler Stages: 28

Assay Type	Results
In situ reporter (knock in)	40
RT-PCR	38

cDNA source data(27)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(28) cDNA(27) Primer pair(1)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000006342 (Evidence)
Ensembl Gene Model	ENSMUSG00000020159 (Evidence)
Entrez Gene	216643 (Evidence)
UniGene	99989
DFCI	TC1580863
DoTS	DT.55214000, DT.60103382
NIA Mouse Gene Index	U032644
Consensus CDS Project	CCDS24535.1
International Mouse Knockout Project Status	Gabrp

Sequences

Length	Strain/Species
genomic	OTTMUSG00000006342	VEGA Gene Model | MGI Sequence Detail	28179	C57BL/6J
transcript	OTTMUST00000014419	VEGA | MGI Sequence Detail	3280	Not Applicable
polypeptide	OTTMUSP00000006688	VEGA | MGI Sequence Detail	440	Not Applicable

All sequences(28) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(66 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR006028	Gamma-aminobutyric acid A receptor
InterPro	IPR008100	Gamma-aminobutyric-acid A receptor pi subunit
InterPro	IPR006201	Neurotransmitter-gated ion-channel
InterPro	IPR018000	Neurotransmitter-gated ion-channel, conserved site
InterPro	IPR006202	Neurotransmitter-gated ion-channel ligand-binding
InterPro	IPR006029	Neurotransmitter-gated ion-channel transmembrane domain
Protein Ontology	PR:000007780	gamma-aminobutyric acid receptor subunit pi

References

(Earliest) J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
(Latest) J:185665 Guo Z, et al., Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20
All references(32)