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Ppp1r9b
Gene Detail
 Symbol
Name
ID
Ppp1r9b
protein phosphatase 1, regulatory subunit 9B
MGI:2387581
Synonyms MGC:38940, neurabin II, spinophilin, SPL, Spn
Feature Type protein coding gene
Genetic Map
Chromosome 11
59.01 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:94991035-95006899 bp, + strand
From VEGA annotation of GRCm38

  15865 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32787  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 dog; 1 zebrafish

Gene Tree: Ppp1r9b

Human
homologs
Human Homolog PPP1R9B, protein phosphatase 1, regulatory subunit 9B
NCBI Gene ID 84687
neXtProt AC  NX_Q96SB3
Human Synonyms  PPP1R6, PPP1R9, SPINO, Spn
Human Chr (Location)  17q21.33; chr17:50133737-50150516 (-)  GRCh38
Alleles
and
phenotypes
All alleles(3) : Targeted(3)
 
Homozygotes for a targeted null mutation exhibit abnormal glutamatergic synaptic transmission, reduced long-term depression, resistance to kainate-induced seizures, impaired taste aversion learning, and increased dendritic spine density.
 
Gene Ontology
(GO)
classifications
All GO classifications: (33 annotations)
Process actin cytoskeleton organization, actin filament organization, ...
Component cell junction, cell projection, ...
Function actin binding, protein binding
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (32)    Tissues (31)    Images (9)
Theiler Stages: 19, 23, 28
Assay TypeResults
RNA in situ 30
Western blot 2
cDNA source data(5)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(6) Genomic(1) cDNA(5)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000001501 (Evidence)
Ensembl Gene ModelENSMUSG00000038976 (Evidence)
Entrez Gene217124 (Evidence)
DFCITC1575930, TC1593490, TC1657211
DoTSDT.110535259, DT.492214, DT.94132931
NIA Mouse Gene IndexU066142
Consensus CDS ProjectCCDS25268.1
International Mouse Knockout Project StatusPpp1r9b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001501 VEGA Gene Model | MGI Sequence Detail 15865 C57BL/6J ±  kb
transcript OTTMUST00000002970 VEGA | MGI Sequence Detail 4508 Not Applicable 
polypeptide OTTMUSP00000001457 VEGA | MGI Sequence Detail 817 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(160 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001478 PDZ domain
Protein Ontology PR:000013133 neurabin-2
References (Earliest) J:77284 Feng J, et al., Spinophilin regulates the formation and function of dendritic spines. Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):9287-92
(Latest) J:193535 Baucum AJ 2nd, et al., Differential association of postsynaptic signaling protein complexes in striatum and hippocampus. J Neurochem. 2013 Feb;124(4):490-501
All references(42)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory