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Cpne2 Gene Detail
Summary
  • Symbol
    Cpne2
  • Name
    copine II
  • Synonyms
    3322401K10Rik, MGC:30751, MGC:30751, MGC:37787
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387578
    NCBI Gene: 234577
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:94532990-94570531 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 46.55 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    195 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2387578
protein coding gene Chr8:94532705-94570531 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033962
protein coding gene Chr8:95961048-95999793 (+)
A/J MGP_AJ_G0033945
protein coding gene Chr8:92220055-92258668 (+)
AKR/J MGP_AKRJ_G0033871
protein coding gene Chr8:94736748-94774260 (+)
BALB/cJ MGP_BALBcJ_G0033937
protein coding gene Chr8:92310824-92348425 (+)
C3H/HeJ MGP_C3HHeJ_G0033647
protein coding gene Chr8:95453528-95492458 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034458
protein coding gene Chr8:99457003-99498488 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031399
protein coding gene Chr8:86023126-86061154 (+)
CAST/EiJ MGP_CASTEiJ_G0032979
protein coding gene Chr8:95036815-95074690 (+)
CBA/J MGP_CBAJ_G0033623
protein coding gene Chr8:102758252-102797710 (+)
DBA/2J MGP_DBA2J_G0033777
protein coding gene Chr8:91688723-91725776 (+)
FVB/NJ MGP_FVBNJ_G0033724
protein coding gene Chr8:90655637-90694008 (+)
LP/J MGP_LPJ_G0033869
protein coding gene Chr8:96103427-96145778 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033766
protein coding gene Chr8:105051042-105090801 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034476
protein coding gene Chr8:94907400-94945874 (+)
PWK/PhJ MGP_PWKPhJ_G0032681
protein coding gene Chr8:91061201-91099782 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032518
protein coding gene Chr8:93728408-93776370 (+)
WSB/EiJ MGP_WSBEiJ_G0033091
protein coding gene Chr8:95433611-95472993 (+)



Homology
more
  • Human Ortholog
    CPNE2, copine 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CPNE2, copine 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    COPN2, CPN2
  • Links
    NCBI Gene ID: 221184
    neXtProt AC: NX_Q96FN4
    UniProt: Q96FN4

  • Chr Location
    16q13; chr16:57092543-57147966 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 27392
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CPNE2
  • Protein SuperFamily
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034361 Ensembl Gene Model | MGI Sequence Detail 37542 C57BL/6J ±  kb
transcript ENSMUST00000048653 Ensembl | MGI Sequence Detail 2342 Not Applicable  
polypeptide ENSMUSP00000045755 Ensembl | MGI Sequence Detail 548 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 17

    Microarray probesets 3
Other
Accession IDs
less
MGI:1913927
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:86882 Creutz CE, et al., The copines, a novel class of C2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved from Paramecium to humans. J Biol Chem. 1998 Jan 16;273(3):1393-402
  • Latest
    J:215487 Thompson CL, et al., A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory