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Wac Gene Detail
Summary
  • Symbol
    Wac
  • Name
    WW domain containing adaptor with coiled-coil
  • Synonyms
    1110067P07Rik, A230035H12Rik, Wwp4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387357
    NCBI Gene: 225131
  • Gene Overview
    MyGene.info: WAC
  • Alliance
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:7868832-7929028 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 4.62 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    346 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2387357
protein coding gene Chr18:7868832-7973547 (.)
129S1/SvImJ MGP_129S1SvImJ_G0024136
protein coding gene Chr18:4757220-4873489 (+)
A/J MGP_AJ_G0024098
protein coding gene Chr18:4791405-4897047 (+)
AKR/J MGP_AKRJ_G0024066
protein coding gene Chr18:4870861-4977568 (+)
BALB/cJ MGP_BALBcJ_G0024098
protein coding gene Chr18:4714971-4818138 (+)
C3H/HeJ MGP_C3HHeJ_G0023864
protein coding gene Chr18:4775033-4882042 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024543
protein coding gene Chr18:5095470-5205554 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021982
protein coding gene Chr18:4453148-4510021 (+)
CAST/EiJ MGP_CASTEiJ_G0023342
protein coding gene Chr18:4777783-4891204 (+)
CBA/J MGP_CBAJ_G0023837
protein coding gene Chr18:5015713-5128452 (+)
DBA/2J MGP_DBA2J_G0023965
protein coding gene Chr18:4608358-4713299 (+)
FVB/NJ MGP_FVBNJ_G0023931
protein coding gene Chr18:4609139-4718088 (+)
LP/J MGP_LPJ_G0024049
protein coding gene Chr18:4799840-4907082 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023959
protein coding gene Chr18:5145456-5261149 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024588
protein coding gene Chr18:4731861-4833253 (+)
PWK/PhJ MGP_PWKPhJ_G0023087
protein coding gene Chr18:4678407-4780919 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022898
protein coding gene Chr18:5007734-5115197 (+)
WSB/EiJ MGP_WSBEiJ_G0023408
protein coding gene Chr18:4722385-4832200 (+)



Homology
more
  • Human Ortholog
    WAC, WW domain containing adaptor with coiled-coil
  • Vertebrate Orthologs
    10
  • Human Ortholog
    WAC, WW domain containing adaptor with coiled-coil
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BM-016, DESSH, PRO1741, Wwp4
  • Links
    NCBI Gene ID: 51322
    neXtProt AC: NX_Q9BTA9
    UniProt: Q9BTA9

  • Chr Location
    10p12.1-p11.2; chr10:28532426-28623112 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 41148
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: WAC
  • Gene Tree
    Wac
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 225131 NCBI Gene Model | MGI Sequence Detail 60197 C57BL/6J ±  kb
transcript NM_153085 RefSeq | MGI Sequence Detail 5217 C57BL/6  
polypeptide Q924H7 UniProt | EBI | MGI Sequence Detail 646 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    cDNA 22

    Microarray probesets 5
Other
Accession IDs
less
MGI:1923581, MGI:2147203, MGI:2147204
References
more
  • Summaries
    All 40
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 13
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265044 Parras A, et al., Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing. Nature. 2018 Aug;560(7719):441-446

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory