About   Help   FAQ
Qsox2 Gene Detail
Summary
  • Symbol
    Qsox2
  • Name
    quiescin Q6 sulfhydryl oxidase 2
  • Synonyms
    Qscn6l1, QSOX2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387194
    NCBI Gene: 227638
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:26209124-26237399 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 18.45 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    128 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2387194
protein coding gene Chr2:26208637-26237525 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025479
protein coding gene Chr2:24160830-24190342 (-)
A/J MGP_AJ_G0025456
protein coding gene Chr2:23226634-23254981 (-)
AKR/J MGP_AKRJ_G0025426
protein coding gene Chr2:23981949-24012322 (-)
BALB/cJ MGP_BALBcJ_G0025452
protein coding gene Chr2:23337771-23366300 (-)
C3H/HeJ MGP_C3HHeJ_G0025213
protein coding gene Chr2:23941859-23970787 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025896
protein coding gene Chr2:24932902-24965411 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023307
protein coding gene Chr2:22109071-22137298 (-)
CAST/EiJ MGP_CASTEiJ_G0024676
protein coding gene Chr2:23811986-23842032 (-)
CBA/J MGP_CBAJ_G0025191
protein coding gene Chr2:25774472-25805762 (-)
DBA/2J MGP_DBA2J_G0025324
protein coding gene Chr2:23052476-23080876 (-)
FVB/NJ MGP_FVBNJ_G0025286
protein coding gene Chr2:22801070-22830658 (-)
LP/J MGP_LPJ_G0025410
protein coding gene Chr2:24096235-24126138 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025317
protein coding gene Chr2:25936819-25966201 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025955
protein coding gene Chr2:23944408-23972660 (-)
PWK/PhJ MGP_PWKPhJ_G0024424
protein coding gene Chr2:22851758-22879868 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024224
protein coding gene Chr2:24073063-24101238 (-)
WSB/EiJ MGP_WSBEiJ_G0024745
protein coding gene Chr2:24049844-24078233 (-)



Homology
more
  • Human Ortholog
    QSOX2, quiescin sulfhydryl oxidase 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    QSOX2, quiescin sulfhydryl oxidase 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    QSCN6L1, SOXN
  • Links
    NCBI Gene ID: 169714
    neXtProt AC: NX_Q6ZRP7
    UniProt: Q6ZRP7

  • Chr Location
    9q34.3; chr9:136206333-136245841 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 227638 NCBI Gene Model | MGI Sequence Detail 28276 C57BL/6J ±  kb
transcript NM_001302956 RefSeq | MGI Sequence Detail 3914 C57BL/6  
polypeptide Q3TMX7 UniProt | EBI | MGI Sequence Detail 692 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 36
    cDNA 36

    Microarray probesets 2
References
more
  • Summaries
    All 29
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:78854 Thorpe C, et al., Sulfhydryl oxidases: emerging catalysts of protein disulfide bond formation in eukaryotes. Arch Biochem Biophys. 2002 Sep 1;405(1):1-12
  • Latest
    J:269310 Wang TE, et al., Mouse quiescin sulfhydryl oxidases exhibit distinct epididymal luminal distribution with segment-specific sperm surface associations. Biol Reprod. 2018 Nov 1;99(5):1022-1033

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2019
MGI 6.14
The Jackson Laboratory