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Zbtb8b Gene Detail
Summary
  • Symbol
    Zbtb8b
  • Name
    zinc finger and BTB domain containing 8b
  • Synonyms
    MGC:38362
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387181
    NCBI Gene: 215627
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:129319558-129334646 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 63.26 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    209 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2387181
 protein coding gene Chr4:129319558-129340761 (-)
129S1/SvImJ ENSMUSG00200018431
 protein coding gene Chr4:122756220-122771286 (-)
A/J ENSMUSG00195036333
 protein coding gene Chr4:124096443-124111527 (-)
AKR/J ENSMUSG00220040617
 protein coding gene Chr4:123087955-123103047 (-)
BALB/cJ ENSMUSG00180040097
 protein coding gene Chr4:121730141-121745225 (-)
C3H/HeJ ENSMUSG00175036113
 protein coding gene Chr4:122742743-122757831 (-)
C57BL/6NJ ENSMUSG00215048144
 protein coding gene Chr4:124243806-124258896 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026519
 protein coding gene Chr4:119231445-119247539 (-)
CAST/EiJ ENSTCUG00005046687
 protein coding gene Chr4:123623915-123638921 (-)
CBA/J ENSMUSG00210053524
 protein coding gene Chr4:122371761-122386845 (-)
DBA/2J ENSMUSG00185049604
 protein coding gene Chr4:123904112-123919200 (-)
FVB/NJ ENSMUSG00205038278
 protein coding gene Chr4:122130800-122145861 (-)
JF1/MsJ ENSUMUG00000022414
 protein coding gene Chr4:124546372-124561476 (-)
LP/J ENSMUSG00230030356
 protein coding gene Chr4:127693681-127708746 (-)
NOD/ShiLtJ ENSMUSG00190041493
 protein coding gene Chr4:122136102-122151159 (-)
NZO/HlLtJ ENSMUSG00225025225
 protein coding gene Chr4:133615046-133630130 (-)
PWK/PhJ ENSLUMG00010040355
 protein coding gene Chr4:121587444-121602545 (-)
SPRET/EiJ ENSMSPG00010042991
 protein coding gene Chr4:123657153-123670769 (-)
WSB/EiJ ENSIUOG00005039535
 protein coding gene Chr4:121991700-122006771 (-)



Homology
more
  • Human Ortholog
    ZBTB8B, zinc finger and BTB domain containing 8B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZBTB8B, zinc finger and BTB domain containing 8B
  • Synonyms
    ZNF916B
  • Links
    NCBI Gene ID: 728116
    UniProt: Q8NAP8

  • Chr Location
    1p35.1; chr1:32465050-32496686 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    658
  • Tissues
    40
  • cDNA Data
    10
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000048485 Ensembl Gene Model | MGI Sequence Detail 15089 C57BL/6J ±  kb
transcript ENSMUST00000106046 Ensembl | MGI Sequence Detail 3323 Not Applicable  
polypeptide ENSMUSP00000101661 Ensembl | MGI Sequence Detail 517 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 10
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:2140532
References
more
  • Summaries
    All 35
    Developmental Gene Expression 5
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:308922 Medeiros de Araujo JA, et al., ZBTB20 is crucial for the specification of a subset of callosal projection neurons and astrocytes in the mammalian neocortex. Development. 2021 Aug 15;148(16):dev196642
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory