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Paip2b Gene Detail
Summary
  • Symbol
    Paip2b
  • Name
    poly(A) binding protein interacting protein 2B
  • Synonyms
    MGC:27648, MGC:49717
  • Feature Type
    protein coding gene
  • IDs
    MGI:2386865
    NCBI Gene: 232164
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:83806058-83831741 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 35.97 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    107 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2386865
protein coding gene Chr6:83805401-83831741 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030942
protein coding gene Chr6:84841133-84869000 (-)
A/J MGP_AJ_G0030911
protein coding gene Chr6:81610536-81636986 (-)
AKR/J MGP_AKRJ_G0030839
protein coding gene Chr6:83971344-83997581 (-)
BALB/cJ MGP_BALBcJ_G0030921
protein coding gene Chr6:81638604-81665784 (-)
C3H/HeJ MGP_C3HHeJ_G0030789
protein coding gene Chr6:100410288-100435545 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031381
protein coding gene Chr6:87186948-87213428 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028567
protein coding gene Chr6:79974812-80003580 (-)
CAST/EiJ MGP_CASTEiJ_G0030030
protein coding gene Chr6:83999074-84025190 (-)
CBA/J MGP_CBAJ_G0030608
protein coding gene Chr6:90609691-90636290 (-)
DBA/2J MGP_DBA2J_G0030761
protein coding gene Chr6:80923768-80950271 (-)
FVB/NJ MGP_FVBNJ_G0030714
protein coding gene Chr6:80135903-80162409 (-)
LP/J MGP_LPJ_G0030840
protein coding gene Chr6:84846901-84873799 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030750
protein coding gene Chr6:94869163-94897620 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031405
protein coding gene Chr6:83802313-83830962 (-)
PWK/PhJ MGP_PWKPhJ_G0029745
protein coding gene Chr6:79843572-79866714 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029573
protein coding gene Chr6:82625301-82651587 (-)
WSB/EiJ MGP_WSBEiJ_G0030111
protein coding gene Chr6:84223880-84248258 (-)



Homology
more
  • Human Ortholog
    PAIP2B, poly(A) binding protein interacting protein 2B
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PAIP2B, poly(A) binding protein interacting protein 2B
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 400961
    neXtProt AC: NX_Q9ULR5
    UniProt: Q9ULR5

  • Chr Location
    2p13.3; chr2:71182738-71227110 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    14 phenotypes from multigenic genotypes
    11 phenotype references
Mice homozygous for a knock-out allele exhibit normal reproductive system physiology.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 232164 NCBI Gene Model | MGI Sequence Detail 25684 C57BL/6J ±  kb
transcript NM_146169 RefSeq | MGI Sequence Detail 3330 C57BL/6  
polypeptide Q91W45 UniProt | EBI | MGI Sequence Detail 136 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 203
    cDNA 203

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:197896 Khoutorsky A, et al., Control of synaptic plasticity and memory via suppression of poly(A)-binding protein. Neuron. 2013 Apr 24;78(2):298-311

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory