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Csrnp2 Gene Detail
Summary
  • Symbol
    Csrnp2
  • Name
    cysteine-serine-rich nuclear protein 2
  • Synonyms
    CSRNP-2, MGC:28165
  • Feature Type
    protein coding gene
  • IDs
    MGI:2386852
    NCBI Gene: 207785
Location & Maps
more
  • Sequence Map
    Chr15:100479570-100495239 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      15670 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 56.32 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    CSRNP2, cysteine and serine rich nuclear protein 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CSRNP2, cysteine and serine rich nuclear protein 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C12orf2, C12orf22, FAM130A1, PPP1R72, TAIP-12
  • Links
    NCBI Gene ID: 81566
    neXtProt AC: NX_Q9H175

  • Chr Location
    12q13.12; chr12:51061205-51083671 (-)  GRCh38.p2
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    5 phenotypes from multigenic genotypes
    25 phenotype references
  • All Mutations and Alleles
    13
  • Chemically induced (other)
    1
  • Gene trapped
    7
  • Radiation induced
    2
  • Targeted
    3
  • Genomic Mutations
    3 involving Csrnp2
  • Incidental Mutations
    APF
Mice homozygous for a knock-out allele are viable, fertile and healthy and display normal development, hematopoiesis and T cell function.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    12
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    15
  • Tissues
    13
  • cDNA Data
    48
  • Literature Summary
    2
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 207785 NCBI Gene Model | MGI Sequence Detail 15670 C57BL/6J ±  kb
transcript NM_153407 RefSeq | MGI Sequence Detail 4126 C57BL/6  
polypeptide Q8BGQ2 UniProt | EBI | MGI Sequence Detail 534 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    106 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000005956 cysteine/serine-rich nuclear protein 2
  • InterPro Domains
    IPR023260 Cysteine/serine-rich nuclear protein family
    IPR031972 Cysteine/serine-rich nuclear protein, N-terminal domain
Molecular
Reagents
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  • All nucleic 49
    cDNA 49

    Microarray probesets 2
References
more
  • Summaries
    All 26
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 3
    Phenotypes 25
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/13/2016
MGI 6.05 		The Jackson Laboratory