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Abca8a Gene Detail
Summary
  • Symbol
    Abca8a
  • Name
    ATP-binding cassette, sub-family A (ABC1), member 8a
  • Feature Type
    protein coding gene
  • IDs
    MGI:2386846
    NCBI Gene: 217258
  • Gene Overview
    MyGene.info: ABCA8
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:110025634-110095978 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 73.07 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    111 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2386846
protein coding gene Chr11:110025634-110097582 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019341
protein coding gene Chr11:113623312-113702285 (-)
A/J MGP_AJ_G0019309
protein coding gene Chr11:108716120-108787536 (-)
AKR/J MGP_AKRJ_G0019278
protein coding gene Chr11:111973280-112042961 (-)
BALB/cJ MGP_BALBcJ_G0019283
protein coding gene Chr11:109131402-109207019 (-)
C3H/HeJ MGP_C3HHeJ_G0019092
protein coding gene Chr11:112253584-112336623 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019733
protein coding gene Chr11:117042857-117126306 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017356
protein coding gene Chr11:105900602-105973744 (-)
CAST/EiJ MGP_CASTEiJ_G0018645
protein coding gene Chr11:113415338-113494425 (-)
CBA/J MGP_CBAJ_G0019061
protein coding gene Chr11:121882412-121964401 (-)
DBA/2J MGP_DBA2J_G0019173
protein coding gene Chr11:108176783-108265204 (-)
FVB/NJ MGP_FVBNJ_G0019164
protein coding gene Chr11:107653753-107724116 (-)
LP/J MGP_LPJ_G0019243
protein coding gene Chr11:114027864-114109012 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019195
protein coding gene Chr11:121007697-121093836 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019770
protein coding gene Chr11:112532048-112605590 (-)
PWK/PhJ MGP_PWKPhJ_G0018410
protein coding gene Chr11:109344125-109417971 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018202
protein coding gene Chr11:112332961-112409975 (-)
WSB/EiJ MGP_WSBEiJ_G0018697
protein coding gene Chr11:112461967-112540437 (-)



Homology
more
  • Human Ortholog
    ABCA8, ATP binding cassette subfamily A member 8
  • Vertebrate Orthologs
    2
  • Human Ortholog
    ABCA8, ATP binding cassette subfamily A member 8
    Orthology source: HGNC
  • Links
    NCBI Gene ID: 10351
    neXtProt AC: NX_O94911
    UniProt: O94911

  • Chr Location
    17q24.2; chr17:68867285-68955426 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000041828 Ensembl Gene Model | MGI Sequence Detail 70345 C57BL/6J ±  kb
transcript ENSMUST00000100287 Ensembl | MGI Sequence Detail 5619 Not Applicable  
polypeptide ENSMUSP00000097860 Ensembl | MGI Sequence Detail 1620 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    cDNA 21
    Primer pair 3

    Microarray probesets 2
References
more
  • Summaries
    All 25
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 2
  • Earliest
    J:73769 Nakamura K, et al., Molecular cloning of a mouse scavenger receptor with C-type lectin (SRCL)(1), a novel member of the scavenger receptor family. Biochim Biophys Acta. 2001 Nov 11;1522(1):53-8
  • Latest
    J:237787 Liu X, et al., Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA. BMC Immunol. 2016 Aug 02;17(1):25

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory