St8sia6
Gene Detail

Symbol Name ID

St8sia6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 MGI:2386797

Synonyms

1700007J08Rik, Siat8f, ST8Sia VI

Feature Type

protein coding gene

Genetic Map

Chromosome 2

10.09 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr2:13651020-13793808 bp, - strand From VEGA annotation of GRCm38   142789 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:17112  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: sialyltransferase
Gene Tree: St8sia6

Human homologs

Human Homolog		ST8SIA6, ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
NCBI Gene ID		338596
neXtProt AC		NX_P61647
Human Synonyms		SIA8F, SIAT8F, ST8SIA-VI
Human Chr (Location)		10p12.33; chr10:17362676-17496254 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(1) : Targeted(1)

Gene Ontology (GO) classifications

All GO classifications: (14 annotations)

Process	carbohydrate biosynthetic process, ganglioside biosynthetic process, ...
Component	Golgi apparatus, integral to Golgi membrane, ...
Function	sialyltransferase activity, transferase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (5 records)
Data Summary: Results (39)    Tissues (31)    Images (17)
Theiler Stages: 12, 13, 14, 23, 28

Assay Type	Results
RNA in situ	39

cDNA source data(11)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(13) cDNA(13)
Microarray probesets(5)

Other database links

VEGA Gene Model	OTTMUSG00000011299 (Evidence)
Ensembl Gene Model	ENSMUSG00000003418 (Evidence)
Entrez Gene	241230 (Evidence)
DFCI	TC1582378, TC1664348
DoTS	DT.101723819, DT.55152706
NIA Mouse Gene Index	U022300, U265727
EC	2.4.99.-
Consensus CDS Project	CCDS15697.1
International Mouse Knockout Project Status	St8sia6

Sequences

Length	Strain/Species
genomic	OTTMUSG00000011299	VEGA Gene Model | MGI Sequence Detail	142789	C57BL/6J
transcript	OTTMUST00000026479	VEGA | MGI Sequence Detail	7363	Not Applicable
polypeptide	OTTMUSP00000012117	VEGA | MGI Sequence Detail	398	Not Applicable

All sequences(34) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(477 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001675	Glycosyl transferase, family 29
InterPro	IPR012163	Sialyltransferase
Protein Ontology	PR:000015700	alpha-2,8-sialyltransferase 8F

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:172805 Wang Q, et al., Recent acquisition of imprinting at the rodent Sfmbt2 locus correlates with insertion of a large block of miRNAs. BMC Genomics. 2011;12:204
All references(35)

Other accession IDs

MGI:1916566, MGI:2138880, MGI:2139109