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Papln Gene Detail
Summary
  • Symbol
    Papln
  • Name
    papilin, proteoglycan-like sulfated glycoprotein
  • Synonyms
    E030033C16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2386139
    NCBI Gene: 170721
  • Gene Overview
    MyGene.info: PAPLN
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:83763634-83792382 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 38.87 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    195 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2386139
protein coding gene Chr12:83762992-83795140 (.)
129S1/SvImJ MGP_129S1SvImJ_G0019917
protein coding gene Chr12:84417419-84446140 (+)
A/J MGP_AJ_G0019874
protein coding gene Chr12:81220810-81249808 (+)
AKR/J MGP_AKRJ_G0019850
protein coding gene Chr12:83422694-83451447 (+)
BALB/cJ MGP_BALBcJ_G0019854
protein coding gene Chr12:81567471-81596653 (+)
C3H/HeJ MGP_C3HHeJ_G0019660
protein coding gene Chr12:83883084-83913576 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020306
protein coding gene Chr12:86832423-86861047 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017923
protein coding gene Chr12:78140746-78169606 (+)
CAST/EiJ MGP_CASTEiJ_G0019209
protein coding gene Chr12:78813570-78844966 (+)
CBA/J MGP_CBAJ_G0019631
protein coding gene Chr12:90172694-90204037 (+)
DBA/2J MGP_DBA2J_G0019746
protein coding gene Chr12:80764649-80793339 (+)
FVB/NJ MGP_FVBNJ_G0019732
protein coding gene Chr12:79713132-79742461 (+)
LP/J MGP_LPJ_G0019818
protein coding gene Chr12:84288913-84317640 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019771
protein coding gene Chr12:93149911-93179268 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020340
protein coding gene Chr12:83009978-83039710 (+)
PWK/PhJ MGP_PWKPhJ_G0018973
protein coding gene Chr12:75236709-75266162 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018768
protein coding gene Chr12:77484081-77515961 (+)
WSB/EiJ MGP_WSBEiJ_G0019261
protein coding gene Chr12:83682536-83711568 (+)



Homology
more
  • Human Ortholog
    PAPLN, papilin, proteoglycan like sulfated glycoprotein
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PAPLN, papilin, proteoglycan like sulfated glycoprotein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PPN
  • Links
    NCBI Gene ID: 89932
    neXtProt AC: NX_O95428
    UniProt: O95428

  • Chr Location
    14q24.2; chr14:73235842-73274640 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000021223 Ensembl Gene Model | MGI Sequence Detail 28749 C57BL/6J ±  kb
    transcript ENSMUST00000121733 Ensembl | MGI Sequence Detail 4373 Not Applicable  
    polypeptide ENSMUSP00000113806 Ensembl | MGI Sequence Detail 1302 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 30
      Genomic 2
      cDNA 27
      Primer pair 1

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2444137
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 4
      Gene Ontology 4
      Phenotypes 10
    • Earliest
      J:74708 Kramerova IA, et al., Papilin in development; a pericellular protein with a homology to the ADAMTS metalloproteinases. Development. 2000 Dec;127(24):5475-85
    • Latest
      J:265604 Naba A, et al., The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices. Mol Cell Proteomics. 2012 Apr;11(4):M111.014647

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    11/13/2018
    MGI 6.13
    The Jackson Laboratory