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C1qtnf5
Gene Detail
Symbol

Name
ID
C1qtnf5
C1q and tumor necrosis factor related protein 5
MGI:2385958
Synonyms
CTRP5
Feature Type
protein coding gene
Genetic Map
Chromosome 9
24.62 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:44107245-44109187 bp, + strand
From VEGA annotation of GRCm38

  1943 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9227  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: C1qtnf5

Human
homologs
Human Homolog C1QTNF5, C1q and tumor necrosis factor related protein 5
NCBI Gene ID 114902
neXtProt AC  NX_Q9BXJ0
Human Synonyms  CTRP5
Human Chr (Location)  11q23.3; chr11:119338934-119346673 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human C1QTNF5
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(1) Targeted(7)
 
Mice heterozygous for a knock-in mouse exhibit increased retina vasculature leakage, retinal degeneration, and features of late-onset macular degeneration. Mice homozygous for the same knock-in generated by a different group are normal.
 
Human Diseases Modeled Using Mouse C1qtnf5 (1)    Alleles Annotated to Human Diseases(1)   
Interactions
C1qtnf5 interacts with 55 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process inner ear development, protein secretion, ...
Component apical plasma membrane, cell, ...
Function identical protein binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (26)    Tissues (2)    Images (15)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 26
cDNA source data(5)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(5) cDNA(5)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000020632 (Evidence)
Ensembl Gene ModelENSMUSG00000079592 (Evidence)
Entrez Gene235312 (Evidence)
Consensus CDS ProjectCCDS52777.1
International Mouse Knockout Project StatusC1qtnf5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020632 VEGA Gene Model | MGI Sequence Detail 1943 C57BL/6J ±  kb
transcript OTTMUST00000048877 VEGA | MGI Sequence Detail 1256 Not Applicable 
polypeptide OTTMUSP00000022526 VEGA | MGI Sequence Detail 243 Not Applicable 

For the selected sequences
All sequences(41) RefSeq(10)
Polymorphisms
SNPs within 2kb(75 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000004887 complement C1q tumor necrosis factor-related protein 5
References
(Earliest) J:78123 Kameya S, et al., Mfrp, a gene encoding a frizzled related protein, is mutated in the mouse retinal degeneration 6. Hum Mol Genet. 2002 Aug 1;11(16):1879-86
(Latest) J:180961 Shu X, et al., Characterisation of a C1qtnf5 Ser163Arg knock-in mouse model of late-onset retinal macular degeneration. PLoS One. 2011;6(11):e27433
All references(34)
Disease annotation references (1)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory