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Defb36 Gene Detail
Summary
  • Symbol
    Defb36
  • Name
    defensin beta 36
  • Synonyms
    Defb123
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385956
    NCBI Gene: 266620
Location & Maps
more
  • Sequence Map
    Chr2:152604327-152612729 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      8403 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 75.41 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    DEFB123, defensin beta 123
  • Vertebrate Orthologs
    2
  • Human Ortholog
    DEFB123, defensin beta 123
    Orthology source: HGNC
  • Synonyms
    DEFB23, DEFB-23, ESC42-RELD
  • Links
    NCBI Gene ID: 245936
    neXtProt AC: NX_Q8N688

  • Chr Location
    20q11.1; chr20:31440519-31450257 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Defb36
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015849 VEGA Gene Model | MGI Sequence Detail 8403 C57BL/6J ±  kb
transcript OTTMUST00000037668 VEGA | MGI Sequence Detail 468 Not Applicable  
polypeptide OTTMUSP00000016891 VEGA | MGI Sequence Detail 67 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    124 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 7
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 22
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:75063 Schutte BC, et al., Discovery of five conserved beta -defensin gene clusters using a computational search strategy. Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):2129-33
  • Latest
    J:162220 Magdaleno S, et al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory