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Hexim1
Gene Detail
Symbol

Name
ID
Hexim1
hexamethylene bis-acetamide inducible 1
MGI:2385923
Synonyms
7330426E13Rik, Clp1, CLP-1, HIS1
Feature Type
protein coding gene
Genetic Map
Chromosome 11
66.71 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:103116231-103119725 bp, + strand
From VEGA annotation of GRCm38

  3495 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:31382  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

HCOP human homology predictions: HEXIM1
Gene Tree: Hexim1

Human
homologs
HEXIM1, hexamethylene bis-acetamide inducible 1
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 10614
neXtProt AC: NX_O94992

Human Synonyms: CLP1, EDG1, HIS1, MAQ1

Human Chr (Location): 17q21.31; chr17:45147317-45152101 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(2) Targeted(3)
Genomic Mutations involving Hexim1 (1)
Incidental mutations (data from CvDC )
 
Mice homozygous for a gene trapped allele exhibit prenatal lethalilty associated with dilated cardiomyopathy.
 
Interactions
Hexim1 interacts with 280 markers (Mir10b, Mir15a, Mir15b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (9 records)
Data Summary: Results (27)    Tissues (18)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 25
Western blot 2
cDNA source data(93)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase LOC100497839    NEW 
Molecular
reagents
All nucleic(94) cDNA(94)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000003296 (Evidence)
Ensembl Gene Model ENSMUSG00000048878 (Evidence)
Entrez Gene 192231 (Evidence)
UniGene 8763
DFCI TC1575781
DoTS DT.531975, DT.101373950
NIA Mouse Gene Index U013411
Consensus CDS Project CCDS25513.1
International Mouse Phenotyping Consortium Status Hexim1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003296 VEGA Gene Model | MGI Sequence Detail 3495 C57BL/6J ±  kb
transcript OTTMUST00000006882 VEGA | MGI Sequence Detail 3495 Not Applicable 
polypeptide OTTMUSP00000003286 VEGA | MGI Sequence Detail 356 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(25 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR024872 HEXIM
Protein Ontology PR:000008526 protein HEXIM1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:208135 Mizutani T, et al., 7SK small nuclear ribonucleoprotein complex is recruited to the HIV-1 promoter via short viral transcripts. FEBS Lett. 2014 May 2;588(9):1630-1636
All references(45)
Other
accession IDs
MGI:1925754

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory