Slc26a1
Gene Detail

Symbol Name ID

Slc26a1 solute carrier family 26 (sulfate transporter), member 1 MGI:2385894

Synonyms

Sat1

Feature Type

protein coding gene

Genetic Map

Chromosome 5

53.24 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr5:108669878-108675569 bp, - strand From VEGA annotation of GRCm38   5692 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:32539  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: sulfate transport protein
Gene Tree: Slc26a1

Human homologs

Human Homolog		SLC26A1, solute carrier family 26 (sulfate transporter), member 1
NCBI Gene ID		10861
neXtProt AC		NX_Q9H2B4
Human Synonyms		EDM4, SAT1, SAT-1
Human Chr (Location)		4p16.3; chr4:972861-987224 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(1) : Targeted(1)
 

Mice homozygous for disruptions in this gene develop kidney stones and have an increased susceptibility to acetaminophen-induced liver damage.

 
Phenotype Images(3)

Gene Ontology (GO) classifications

All GO classifications: (16 annotations)

Process	chloride transport, ion transmembrane transport, ...
Component	integral to membrane, membrane
Function	chloride transmembrane transporter activity, oxalate transmembrane transporter activity, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (118)    Tissues (95)    Images (28)
Theiler Stages: 22, 23

Assay Type	Results
RNA in situ	118

cDNA source data(25)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(26) cDNA(25) Primer pair(1)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000027011 (Evidence)
Ensembl Gene Model	ENSMUSG00000046959 (Evidence)
Entrez Gene	231583 (Evidence)
UniGene	440571
DFCI	TC1580138
DoTS	DT.50315497, DT.87050160, DT.97405813
NIA Mouse Gene Index	U026535
Consensus CDS Project	CCDS19517.1
International Mouse Knockout Project Status	Slc26a1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000027011	VEGA Gene Model | MGI Sequence Detail	5692	C57BL/6J
transcript	OTTMUST00000066778	VEGA | MGI Sequence Detail	3031	Not Applicable
polypeptide	OTTMUSP00000033513	VEGA | MGI Sequence Detail	720	Not Applicable

All sequences(43) RefSeq(2) UniProt(7)

Polymorphisms

SNPs(26 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR002645	STAS domain
InterPro	IPR001902	Sulphate anion transporter
InterPro	IPR018045	Sulphate anion transporter, conserved site
InterPro	IPR011547	Sulphate transporter
Protein Ontology	PR:000015035	sulfate anion transporter 1

References

(Earliest) J:81718 Lee A, et al., The mouse sulfate anion transporter gene sat1 (slc26a1): cloning, tissue distribution, gene structure, functional characterization, and transcriptional regulation thyroid hormone. DNA Cell Biol. 2003 Jan;22(1):19-31
(Latest) J:192414 Dawson PA, et al., Placental, renal, and ileal sulfate transporter gene expression in mouse gestation. Biol Reprod. 2012 Aug;87(2):43
All references(30)