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Slc26a1
Gene Detail
Symbol

Name
ID
Slc26a1
solute carrier family 26 (sulfate transporter), member 1
MGI:2385894
Synonyms
Sat1
Feature Type
protein coding gene
Genetic Map
Chromosome 5
53.24 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr5:108669878-108675569 bp, - strand
From VEGA annotation of GRCm38

  5692 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32539  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: sulfate transport protein
Gene Tree: Slc26a1

Human
homologs
Human Homolog SLC26A1, solute carrier family 26 (anion exchanger), member 1
NCBI Gene ID 10861
neXtProt AC  NX_Q9H2B4
Human Synonyms  EDM4, SAT1, SAT-1
Human Chr (Location)  4p16.3; chr4:979073-994198 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for disruptions in this gene develop kidney stones and have an increased susceptibility to acetaminophen-induced liver damage.
 
Phenotype Images(3)
Interactions
Slc26a1 interacts with 245 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process chloride transmembrane transport, chloride transport, ...
Component integral component of membrane, membrane
Function anion:anion antiporter activity, antiporter activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (118)    Tissues (95)    Images (28)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 118
cDNA source data(26)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(27) cDNA(26) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000027011 (Evidence)
Ensembl Gene ModelENSMUSG00000046959 (Evidence)
Entrez Gene231583 (Evidence)
UniGene440571
DFCITC1580138
DoTSDT.50315497, DT.87050160, DT.97405813
NIA Mouse Gene IndexU026535
Consensus CDS ProjectCCDS19517.1
International Mouse Knockout Project StatusSlc26a1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027011 VEGA Gene Model | MGI Sequence Detail 5692 C57BL/6J ±  kb
transcript OTTMUST00000066778 VEGA | MGI Sequence Detail 3031 Not Applicable 
polypeptide OTTMUSP00000033513 VEGA | MGI Sequence Detail 720 Not Applicable 

For the selected sequences
All sequences(59) RefSeq(14) UniProt(11)
Polymorphisms
SNPs within 2kb(40 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002645 STAS domain
InterPro IPR001902 Sulphate anion transporter
InterPro IPR018045 Sulphate anion transporter, conserved site
InterPro IPR011547 Sulphate transporter
Protein Ontology PR:000015035 sulfate anion transporter 1
References
(Earliest) J:79463 Xie Q, et al., Molecular characterization of the murine Slc26a6 anion exchanger: functional comparison with Slc26a1. Am J Physiol Renal Physiol. 2002 Oct;283(4):F826-38
(Latest) J:192414 Dawson PA, et al., Placental, renal, and ileal sulfate transporter gene expression in mouse gestation. Biol Reprod. 2012 Aug;87(2):43
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory