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Ddx27 Gene Detail
Summary
  • Symbol
    Ddx27
  • Name
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385884
    NCBI Gene: 228889
  • Gene Overview
    MyGene.info: DDX27
Location & Maps
more
  • Sequence Map
    Chr2:167015193-167034947 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      19755 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 87.22 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    DDX27, DEAD-box helicase 27
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DDX27, DEAD-box helicase 27
    Orthology source: HomoloGene
  • Synonyms
    dJ686N3.1, DRS1, Drs1p, HSPC259, PP3241, RHLP
  • Links
    NCBI Gene ID: 55661
    neXtProt AC: NX_Q96GQ7

  • Chr Location
    20q13.13; chr20:49219295-49244077 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    20
  • Gene trapped
    18
  • Targeted
    2
  • Incidental Mutations
    APF , CvDC
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001151 VEGA Gene Model | MGI Sequence Detail 19755 C57BL/6J ±  kb
transcript OTTMUST00000002243 VEGA | MGI Sequence Detail 2714 Not Applicable  
polypeptide OTTMUSP00000001092 VEGA | MGI Sequence Detail 760 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    107 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • EC
  • InterPro Domains
    IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site
    IPR011545 DEAD/DEAH box helicase domain
    IPR001650 Helicase, C-terminal
    IPR014001 Helicase superfamily 1/2, ATP-binding domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR014014 RNA helicase, DEAD-box type, Q motif
Molecular
Reagents
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  • All nucleic 103
    cDNA 103

    Microarray probesets 5
Other
Accession IDs
less
MGI:2139524
References
more
  • Summaries
    All 32
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory