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Ddx27
Gene Detail
Symbol

Name
ID
Ddx27
DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
MGI:2385884
Feature Type
protein coding gene
Genetic Map
Chromosome 2
87.22 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:167015193-167034947 bp, + strand
From VEGA annotation of GRCm38

  19755 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6431  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: DDX27
Protein SuperFamily: ATP-dependent RNA helicase
Gene Tree: Ddx27

Human
homologs
DDX27, DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 55661
neXtProt AC: NX_Q96GQ7

Human Synonyms: dJ686N3.1, DRS1, Drs1p, HSPC259, PP3241, RHLP

Human Chr (Location): 20q13.13; chr20:49219295-49244077 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(20) : Gene trapped(18) Targeted(2)
Incidental mutations (data from APF , CvDC )
Interactions
Ddx27 interacts with 147 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process RNA secondary structure unwinding
Component nucleus
Function ATP binding, ATP-dependent RNA helicase activity, ...
External Resources: FuncBase
Expression
cDNA source data(103)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA DDX27 ; Xenbase ddx27 ; ZFIN ddx27    NEW 
Molecular
reagents
All nucleic(103) cDNA(103)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000001151 (Evidence)
Ensembl Gene Model ENSMUSG00000017999 (Evidence)
Entrez Gene 228889 (Evidence)
UniGene 295031
DFCI TC1574944, TC1655353
DoTS DT.50317110, DT.101390962
NIA Mouse Gene Index U002845
EC 3.6.4.13
Consensus CDS Project CCDS38336.1
International Mouse Phenotyping Consortium Status Ddx27
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001151 VEGA Gene Model | MGI Sequence Detail 19755 C57BL/6J ±  kb
transcript OTTMUST00000002243 VEGA | MGI Sequence Detail 2714 Not Applicable 
polypeptide OTTMUSP00000001092 VEGA | MGI Sequence Detail 760 Not Applicable 

For the selected sequences
All sequences(55) RefSeq(4) UniProt(2)
Polymorphisms
SNPs within 2kb(107 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011545 DNA/RNA helicase, DEAD/DEAH box type, N-terminal
InterPro IPR001650 Helicase, C-terminal
InterPro IPR014001 Helicase, superfamily 1/2, ATP-binding domain
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR000629 RNA helicase, ATP-dependent, DEAD-box, conserved site
InterPro IPR014014 RNA helicase, DEAD-box type, Q motif
Protein Ontology PR:000029386 ATP-dependent RNA helicase DDX27
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(37)
Other
accession IDs
MGI:2139524

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory