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Ddx27 Gene Detail
Summary
  • Symbol
    Ddx27
  • Name
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385884
    NCBI Gene: 228889
  • Gene Overview
    MyGene.info: DDX27
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:167015255-167034950 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 87.22 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    107 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385884
protein coding gene Chr2:167015193-167034950 (.)
129S1/SvImJ MGP_129S1SvImJ_G0026906
protein coding gene Chr2:172713688-172734514 (+)
A/J MGP_AJ_G0026873
protein coding gene Chr2:165619359-165639498 (+)
AKR/J MGP_AKRJ_G0026844
protein coding gene Chr2:170547395-170570119 (+)
BALB/cJ MGP_BALBcJ_G0026882
protein coding gene Chr2:165968402-165988537 (+)
C3H/HeJ MGP_C3HHeJ_G0026624
protein coding gene Chr2:170916482-170938036 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027329
protein coding gene Chr2:177733958-177753414 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024700
protein coding gene Chr2:158946035-158966584 (+)
CAST/EiJ MGP_CASTEiJ_G0026082
protein coding gene Chr2:171374220-171395912 (+)
CBA/J MGP_CBAJ_G0026601
protein coding gene Chr2:184251100-184275823 (+)
DBA/2J MGP_DBA2J_G0026739
protein coding gene Chr2:164740172-164760325 (+)
FVB/NJ MGP_FVBNJ_G0026705
protein coding gene Chr2:163245577-163265832 (+)
LP/J MGP_LPJ_G0026840
protein coding gene Chr2:172739187-172758564 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026724
protein coding gene Chr2:187655500-187677198 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027386
protein coding gene Chr2:170457216-170478353 (+)
PWK/PhJ MGP_PWKPhJ_G0025819
protein coding gene Chr2:164391665-164412453 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025620
protein coding gene Chr2:169401095-169422140 (+)
WSB/EiJ MGP_WSBEiJ_G0026155
protein coding gene Chr2:171360139-171380830 (+)



Homology
more
  • Human Ortholog
    DDX27, DEAD-box helicase 27
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DDX27, DEAD-box helicase 27
    Orthology source: HomoloGene, HGNC
  • Synonyms
    dJ686N3.1, DRS1, Drs1p, HSPC259, PP3241, RHLP
  • Links
    NCBI Gene ID: 55661
    neXtProt AC: NX_Q96GQ7
    UniProt: Q96GQ7

  • Chr Location
    20q13.13; chr20:49219295-49244077 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 228889 NCBI Gene Model | MGI Sequence Detail 19696 C57BL/6J ±  kb
transcript NM_153065 RefSeq | MGI Sequence Detail 2592 C57BL/6  
polypeptide Q921N6 UniProt | EBI | MGI Sequence Detail 760 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • EC
  • InterPro Domains
    IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site
    IPR011545 DEAD/DEAH box helicase domain
    IPR001650 Helicase, C-terminal
    IPR014001 Helicase superfamily 1/2, ATP-binding domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR014014 RNA helicase, DEAD-box type, Q motif
Molecular
Reagents
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  • All nucleic 104
    cDNA 104

    Microarray probesets 5
Other
Accession IDs
less
MGI:2139524
References
more
  • Summaries
    All 31
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:243553 Fisher CL, et al., An efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers. Nucleic Acids Res. 2017 Dec 1;45(21):e174

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory