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Bcas3 Gene Detail
Summary
  • Symbol
    Bcas3
  • Name
    breast carcinoma amplified sequence 3
  • Synonyms
    1500019F07Rik, 2610028P08Rik, K20D4, rudhira
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385848
    NCBI Gene: 192197
  • Gene Overview
    MyGene.info: BCAS3
Location & Maps
more
  • Sequence Map
    Chr11:85353167-85826058 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      472892 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 51.34 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    BCAS3, BCAS3, microtubule associated cell migration factor
  • Vertebrate Orthologs
    10
  • Human Ortholog
    BCAS3, BCAS3, microtubule associated cell migration factor
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GAOB1, MAAB
  • Links
    NCBI Gene ID: 54828
    neXtProt AC: NX_Q9H6U6

  • Chr Location
    17q23; chr17:60677811-61392838 (+)  GRCh38.p2
  • HomoloGene
    Vertebrate Homology Class 9778
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: BCAS3
  • Gene Tree
    Bcas3
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
  • All Mutations and Alleles
    53
  • Chemically induced (other)
    1
  • Gene trapped
    51
  • Targeted
    1
  • Genomic Mutations
    2 involving Bcas3
  • Incidental Mutations
    Mutagenetix , APF
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    37
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    83
  • Tissues
    37
  • cDNA Data
    96
  • Literature Summary
    1
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001026 VEGA Gene Model | MGI Sequence Detail 472892 C57BL/6J ±  kb
transcript OTTMUST00000002042 VEGA | MGI Sequence Detail 3810 Not Applicable  
polypeptide OTTMUSP00000000985 VEGA | MGI Sequence Detail 943 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    2422 from dbSNP Build 142
Protein
Information
less
  • UniProt
    10 Sequences
  • Protein Ontology
    PR:000004680 breast carcinoma-amplified sequence 3
  • InterPro Domains
    IPR022175 Breast carcinoma amplified sequence 3
    IPR017986 WD40-repeat-containing domain
    IPR015943 WD40/YVTN repeat-like-containing domain
Molecular
Reagents
less
  • All nucleic 98
    cDNA 96
    Primer pair 2

    Microarray probesets 6
Other
Accession IDs
less
MGI:1917451, MGI:1923594, MGI:2144406
References
more
  • Summaries
    All 36
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 13
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:212786 Jain M, et al., Rudhira/BCAS3 is a cytoskeletal protein that controls Cdc42 activation and directional cell migration during angiogenesis. Exp Cell Res. 2012 Apr 1;318(6):753-67
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/20/2016
MGI 6.05 		The Jackson Laboratory