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Bcas3
Gene Detail
Symbol

Name
ID
Bcas3
breast carcinoma amplified sequence 3
MGI:2385848
Synonyms
1500019F07Rik, 2610028P08Rik, K20D4, rudhira
Feature Type
protein coding gene
Genetic Map
Chromosome 11
51.34 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:85353167-85826058 bp, + strand
From VEGA annotation of GRCm38

  472892 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9778  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Bcas3

Human
homologs
Human Homolog BCAS3, breast carcinoma amplified sequence 3
NCBI Gene ID 54828
neXtProt AC  NX_Q9H6U6
Human Synonyms  GAOB1, MAAB
Human Chr (Location)  17q23; chr17:60677811-61392838 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(51) : Gene trapped(51)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Bcas3 interacts with 201 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (36 annotations)
Process activation of Cdc42 GTPase activity, angiogenesis, ...
Component cell leading edge, cell periphery, ...
Function acetyltransferase activator activity, beta-tubulin binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (83)    Tissues (37)    Images (30)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 18
RNA in situ 29
RT-PCR 36
cDNA source data(96)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(98) cDNA(96) Primer pair(2)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000001026 (Evidence)
Ensembl Gene ModelENSMUSG00000059439 (Evidence)
Entrez Gene192197 (Evidence)
UniGene287663
DFCITC1639324, TC1686574, TC1630610, TC1575651, TC1599600, TC1591659, TC1630934
DoTSDT.101366697, DT.101400029, DT.530548, DT.40145677, DT.94290885, DT.524620, DT.40136642, DT.110519137
NIA Mouse Gene IndexU013121
Consensus CDS ProjectCCDS25195.1, CCDS48873.1
International Mouse Knockout Project StatusBcas3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001026 VEGA Gene Model | MGI Sequence Detail 472892 C57BL/6J ±  kb
transcript OTTMUST00000002042 VEGA | MGI Sequence Detail 3810 Not Applicable 
polypeptide OTTMUSP00000000985 VEGA | MGI Sequence Detail 943 Not Applicable 

For the selected sequences
All sequences(138) RefSeq(21) UniProt(19)
Polymorphisms
SNPs within 2kb(2433 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR022175 Breast carcinoma amplified sequence 3
InterPro IPR001680 WD40 repeat
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000004680 breast carcinoma-amplified sequence 3
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:212786 Jain M, et al., Rudhira/BCAS3 is a cytoskeletal protein that controls Cdc42 activation and directional cell migration during angiogenesis. Exp Cell Res. 2012 Apr 1;318(6):753-67
All references(41)
Other
accession IDs
MGI:1917451, MGI:1923594, MGI:2144406

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory