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Mical1 Gene Detail
Summary
  • Symbol
    Mical1
  • Name
    microtubule associated monooxygenase, calponin and LIM domain containing 1
  • Synonyms
    MGC:27831, MGC:38321, Nical
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385847
    NCBI Gene: 171580
  • Gene Overview
    MyGene.info: MICAL1
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:41476314-41487032 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 22.41 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    81 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385847
protein coding gene Chr10:41475860-41487032 (.)
129S1/SvImJ MGP_129S1SvImJ_G0017173
protein coding gene Chr10:40118208-40128922 (+)
A/J MGP_AJ_G0017150
protein coding gene Chr10:39000661-39011379 (+)
AKR/J MGP_AKRJ_G0017110
protein coding gene Chr10:39586037-39596755 (+)
BALB/cJ MGP_BALBcJ_G0017112
protein coding gene Chr10:39069621-39080339 (+)
C3H/HeJ MGP_C3HHeJ_G0016933
protein coding gene Chr10:39901555-39912276 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017571
protein coding gene Chr10:41341261-41352086 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015267
protein coding gene Chr10:36938394-36949291 (+)
CAST/EiJ MGP_CASTEiJ_G0016512
protein coding gene Chr10:40102857-40113722 (+)
CBA/J MGP_CBAJ_G0016907
protein coding gene Chr10:43226398-43237116 (+)
DBA/2J MGP_DBA2J_G0017012
protein coding gene Chr10:38504709-38515427 (+)
FVB/NJ MGP_FVBNJ_G0017007
protein coding gene Chr10:38004268-38014986 (+)
LP/J MGP_LPJ_G0017089
protein coding gene Chr10:40106241-40116955 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017037
protein coding gene Chr10:44050131-44060849 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017608
protein coding gene Chr10:39567193-39577911 (+)
PWK/PhJ MGP_PWKPhJ_G0016292
protein coding gene Chr10:38381086-38392058 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016076
protein coding gene Chr10:39382938-39393701 (+)
WSB/EiJ MGP_WSBEiJ_G0016575
protein coding gene Chr10:39892724-39903473 (+)



Homology
more
  • Human Ortholog
    MICAL1, microtubule associated monooxygenase, calponin and LIM domain containing 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    MICAL1, microtubule associated monooxygenase, calponin and LIM domain containing 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MICAL, MICAL-1, NICAL
  • Links
    NCBI Gene ID: 64780
    neXtProt AC: NX_Q8TDZ2
    UniProt: Q8TDZ2

  • Chr Location
    6q21; chr6:109444062-109465968 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000019823 Ensembl Gene Model | MGI Sequence Detail 10719 C57BL/6J ±  kb
transcript ENSMUST00000119962 Ensembl | MGI Sequence Detail 3565 Not Applicable  
polypeptide ENSMUSP00000113783 Ensembl | MGI Sequence Detail 1048 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 60
    cDNA 60

    Microarray probesets 4
References
more
  • Summaries
    All 41
    Developmental Gene Expression 1
    Gene Ontology 8
    Phenotypes 12
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:266107 Alqassim SS, et al., Modulation of MICAL Monooxygenase Activity by its Calponin Homology Domain: Structural and Mechanistic Insights. Sci Rep. 2016 Mar 3;6:22176

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory