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Plekhb2 Gene Detail
Summary
  • Symbol
    Plekhb2
  • Name
    pleckstrin homology domain containing, family B (evectins) member 2
  • Synonyms
    2310009M15Rik, evt-2, Phdc
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385825
    NCBI Gene: 226971
  • Gene Overview
    MyGene.info: PLEKHB2
Location & Maps
more
  • Sequence Map
    Chr1:34849976-34879580 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      29605 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 13.34 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    PLEKHB2, pleckstrin homology domain containing B2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PLEKHB2, pleckstrin homology domain containing B2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    EVT2
  • Links
    NCBI Gene ID: 55041
    neXtProt AC: NX_Q96CS7
    UniProt: Q96CS7

  • Chr Location
    2q21.1; chr2:131104847-131149852 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    184
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029565 VEGA Gene Model | MGI Sequence Detail 29605 C57BL/6J ±  kb
transcript OTTMUST00000073322 VEGA | MGI Sequence Detail 3279 Not Applicable  
polypeptide OTTMUSP00000037926 VEGA | MGI Sequence Detail 221 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    174 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 184
    cDNA 184

    Microarray probesets 4
Other
Accession IDs
less
MGI:1924835, MGI:2138415
References
more
  • Summaries
    All 31
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:78057 Krappa R, et al., Evectins: vesicular proteins that carry a pleckstrin homology domain and localize to post-Golgi membranes. Proc Natl Acad Sci U S A. 1999 Apr 13;96(8):4633-8
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
06/20/2017
MGI 6.10 		The Jackson Laboratory