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Shkbp1 Gene Detail
Summary
  • Symbol
    Shkbp1
  • Name
    Sh3kbp1 binding protein 1
  • Synonyms
    B930062H15Rik, SB1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385803
    NCBI Gene: 192192
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:27342133-27356019 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 15.88 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    121 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385803
protein coding gene Chr7:27342128-27356019 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031908
protein coding gene Chr7:25982479-25998814 (-)
A/J MGP_AJ_G0031887
protein coding gene Chr7:25362279-25375955 (-)
AKR/J MGP_AKRJ_G0031817
protein coding gene Chr7:26031225-26044805 (-)
BALB/cJ MGP_BALBcJ_G0031892
protein coding gene Chr7:25581067-25594834 (-)
C3H/HeJ MGP_C3HHeJ_G0031614
protein coding gene Chr7:26413195-26430578 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032357
protein coding gene Chr7:26836036-26854085 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029409
protein coding gene Chr7:26596058-26610340 (-)
CAST/EiJ MGP_CASTEiJ_G0030949
protein coding gene Chr7:19719204-19735457 (-)
CBA/J MGP_CBAJ_G0031579
protein coding gene Chr7:28028220-28044969 (-)
DBA/2J MGP_DBA2J_G0031731
protein coding gene Chr7:25159389-25173394 (-)
FVB/NJ MGP_FVBNJ_G0031687
protein coding gene Chr7:25249536-25266937 (-)
LP/J MGP_LPJ_G0031811
protein coding gene Chr7:26312625-26327546 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031722
protein coding gene Chr7:27610005-27627571 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032388
protein coding gene Chr7:25572552-25587607 (-)
PWK/PhJ MGP_PWKPhJ_G0030673
protein coding gene Chr7:20196613-20210658 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030507
protein coding gene Chr7:16560680-16575614 (-)
WSB/EiJ MGP_WSBEiJ_G0031057
protein coding gene Chr7:25856308-25871620 (-)



Homology
more
  • Human Ortholog
    SHKBP1, SH3KBP1 binding protein 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    SHKBP1, SH3KBP1 binding protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PP203, Sb1
  • Links
    NCBI Gene ID: 92799
    neXtProt AC: NX_Q8TBC3
    UniProt: Q8TBC3

  • Chr Location
    19q13.2; chr19:40576851-40591399 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000089832 Ensembl Gene Model | MGI Sequence Detail 13887 C57BL/6J ±  kb
transcript ENSMUST00000003857 Ensembl | MGI Sequence Detail 2358 Not Applicable  
polypeptide ENSMUSP00000003857 Ensembl | MGI Sequence Detail 704 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 4
Other
Accession IDs
less
MGI:2444000
References
more
  • Summaries
    All 26
    Gene Ontology 6
    Phenotypes 3
  • Earliest
    J:76181 Borinstein SC, et al., SETA is a multifunctional adapter protein with three SH3 domains that binds Grb2, Cbl, and the novel SB1 proteins. Cell Signal. 2000 Dec;12(11-12):769-79
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/26/2019
MGI 6.14
The Jackson Laboratory