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Shkbp1 Gene Detail
Summary
  • Symbol
    Shkbp1
  • Name
    Sh3kbp1 binding protein 1
  • Synonyms
    B930062H15Rik, SB1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385803
    NCBI Gene: 192192
Location & Maps
more
  • Sequence Map
    Chr7:27342133-27356019 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      13887 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 15.88 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    SHKBP1, SH3KBP1 binding protein 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    SHKBP1, SH3KBP1 binding protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PP203, Sb1
  • Links
    NCBI Gene ID: 92799
    neXtProt AC: NX_Q8TBC3

  • Chr Location
    19q13.2; chr19:40576851-40591399 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023744 VEGA Gene Model | MGI Sequence Detail 13887 C57BL/6J ±  kb
transcript OTTMUST00000057992 VEGA | MGI Sequence Detail 2358 Not Applicable  
polypeptide OTTMUSP00000028049 VEGA | MGI Sequence Detail 704 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    121 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 4
Other
Accession IDs
less
MGI:2444000
References
more
  • Summaries
    All 24
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:76181 Borinstein SC, et al., SETA is a multifunctional adapter protein with three SH3 domains that binds Grb2, Cbl, and the novel SB1 proteins. Cell Signal. 2000 Dec;12(11-12):769-79
  • Latest
    J:227464 Feng L, et al., SH3KBP1-binding protein 1 prevents epidermal growth factor receptor degradation by the interruption of c-Cbl-CIN85 complex. Cell Biochem Funct. 2011 Oct;29(7):589-96

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory