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Acsbg1
Gene Detail
Symbol

Name
ID
Acsbg1
acyl-CoA synthetase bubblegum family member 1
MGI:2385656
Synonyms
BG1, Bgm, E230019G03Rik, GR-LACS, Lpd, mKIAA0631
Feature Type
protein coding gene
Genetic Map
Chromosome 9
29.70 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr9:54604877-54661870 bp, - strand
From VEGA annotation of GRCm38

  56994 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9044  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: ACSBG1
Gene Tree: Acsbg1

Human
homologs
ACSBG1, acyl-CoA synthetase bubblegum family member 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 23205
neXtProt AC: NX_Q96GR2

Human Synonyms: BG, BG1, BGM, GR-LACS, LPD

Human Chr (Location): 15q23-q24; chr15:78170845-78234707 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(2) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null mutation display abnormalities in gonadotropin induced changes in testosterone production, Leydig cell morphology and long chain and very long chain fatty acid levels.
 
Interactions
Acsbg1 interacts with 102 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (25 annotations)
Process fatty acid metabolic process, lipid metabolic process, ...
Component cytoplasm, cytoplasmic vesicle, ...
Function ATP binding, catalytic activity, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (350)    Tissues (153)    Images (47)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 324
Northern blot 20
RT-PCR 6
cDNA source data(40)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase acsbg1    NEW 
Molecular
reagents
All nucleic(42) cDNA(40) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000030280 (Evidence)
Ensembl Gene Model ENSMUSG00000032281 (Evidence)
Entrez Gene 94180 (Evidence)
UniGene 20592
DFCI TC1572411
DoTS DT.528603
NIA Mouse Gene Index U030885
EC 6.2.1.3
Consensus CDS Project CCDS23192.1
International Mouse Phenotyping Consortium Status Acsbg1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030280 VEGA Gene Model | MGI Sequence Detail 56994 C57BL/6J ±  kb
transcript OTTMUST00000074956 VEGA | MGI Sequence Detail 2880 Not Applicable 
polypeptide OTTMUSP00000039208 VEGA | MGI Sequence Detail 721 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(6) UniProt(4)
Polymorphisms
SNPs within 2kb(526 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR020845 AMP-binding, conserved site
InterPro IPR000873 AMP-dependent synthetase/ligase
Protein Ontology PR:000003655 long-chain-fatty-acid--CoA ligase ACSBG1
References
(Earliest) J:71861 Moriya-Sato A, et al., Novel acyl-CoA synthetase in adrenoleukodystrophy target tissues. Biochem Biophys Res Commun. 2000 Dec 9;279(1):62-8
(Latest) J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
All references(40)
Disease annotation references (1)
Other
accession IDs
MGI:2143449

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory