Acsbg1
Gene Detail

Symbol Name ID

Acsbg1 acyl-CoA synthetase bubblegum family member 1 MGI:2385656

Synonyms

BG1, Bgm, E230019G03Rik, GR-LACS, Lpd, mKIAA0631

Feature Type

protein coding gene

Genetic Map

Chromosome 9

29.70 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr9:54604877-54661870 bp, - strand From VEGA annotation of GRCm38   56994 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:9044  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Acsbg1

Human homologs

Human Homolog		ACSBG1, acyl-CoA synthetase bubblegum family member 1
NCBI Gene ID		23205
neXtProt AC		NX_Q96GR2
Human Synonyms		BG, BG1, BGM, GR-LACS, LPD
Human Chr (Location)		15q23-q24; chr15:78170845-78234707 (-)  GRCh38

Alleles and phenotypes

All alleles(5) : Gene trapped(2) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 

Mice homozygous for a null mutation display abnormalities in gonadotropin induced changes in testosterone production, Leydig cell morphology and long chain and very long chain fatty acid levels.

 

Gene Ontology (GO) classifications

All GO classifications: (25 annotations)

Process	fatty acid metabolic process, lipid metabolic process, ...
Component	cytoplasm, cytoplasmic vesicle, ...
Function	ATP binding, catalytic activity, ...

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (5 records)

Data Summary: Results (350)    Tissues (152)    Images (47)
Theiler Stages: 19, 20, 22, 23, 26, 28

Assay Type	Results
RNA in situ	324
Northern blot	20
RT-PCR	6

cDNA source data(40)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress

Molecular reagents

All nucleic(42) cDNA(40) Primer pair(2)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000030280 (Evidence)
Ensembl Gene Model	ENSMUSG00000032281 (Evidence)
Entrez Gene	94180 (Evidence)
UniGene	20592
DFCI	TC1572411
DoTS	DT.528603
NIA Mouse Gene Index	U030885
EC	6.2.1.3
Consensus CDS Project	CCDS23192.1
International Mouse Knockout Project Status	Acsbg1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000030280	VEGA Gene Model | MGI Sequence Detail	56994	C57BL/6J
transcript	OTTMUST00000074956	VEGA | MGI Sequence Detail	2880	Not Applicable
polypeptide	OTTMUSP00000039208	VEGA | MGI Sequence Detail	721	Not Applicable

All sequences(43) RefSeq(6) UniProt(4)

Polymorphisms

SNPs within 2kb(526 from dbSNP Build 137)

Protein-related information

Resource	ID	Description
InterPro	IPR020845	AMP-binding, conserved site
InterPro	IPR000873	AMP-dependent synthetase/ligase
Protein Ontology	PR:000003655	long-chain-fatty-acid--CoA ligase ACSBG1

References

(Earliest) J:71861 Moriya-Sato A, et al., Novel acyl-CoA synthetase in adrenoleukodystrophy target tissues. Biochem Biophys Res Commun. 2000 Dec 9;279(1):62-8
(Latest) J:188328 Li X, et al., MEK Is a Key Regulator of Gliogenesis in the Developing Brain. Neuron. 2012 Sep 20;75(6):1035-50
All references(41)

Other accession IDs

MGI:2143449