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Nup153 Gene Detail
Summary
  • Symbol
    Nup153
  • Name
    nucleoporin 153
  • Synonyms
    B130015D15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385621
    NCBI Gene: 218210
  • Gene Overview
    MyGene.info: NUP153
  • Alliance
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:46679902-46727849 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 24.30 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    147 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385621
protein coding gene Chr13:46679902-46727940 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020515
protein coding gene Chr13:45454846-45503648 (-)
A/J MGP_AJ_G0020469
protein coding gene Chr13:43880821-43929067 (-)
AKR/J MGP_AKRJ_G0020446
protein coding gene Chr13:45085451-45136508 (-)
BALB/cJ MGP_BALBcJ_G0020465
protein coding gene Chr13:44087961-44136452 (-)
C3H/HeJ MGP_C3HHeJ_G0020264
protein coding gene Chr13:44953837-45002189 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020898
protein coding gene Chr13:46840606-46890720 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018483
protein coding gene Chr13:41916501-41968725 (-)
CAST/EiJ MGP_CASTEiJ_G0019779
protein coding gene Chr13:44881578-44932291 (-)
CBA/J MGP_CBAJ_G0020225
protein coding gene Chr13:48790339-48842527 (-)
DBA/2J MGP_DBA2J_G0020347
protein coding gene Chr13:43438172-43486318 (-)
FVB/NJ MGP_FVBNJ_G0020326
protein coding gene Chr13:42954641-43002901 (-)
LP/J MGP_LPJ_G0020422
protein coding gene Chr13:45688654-45737285 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020355
protein coding gene Chr13:48611820-48662390 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020941
protein coding gene Chr13:44766423-44815877 (-)
PWK/PhJ MGP_PWKPhJ_G0019535
protein coding gene Chr13:43563556-43612374 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019363
protein coding gene Chr13:43437239-43484553 (-)
WSB/EiJ MGP_WSBEiJ_G0019841
protein coding gene Chr13:45098059-45146582 (-)



Homology
more
  • Human Ortholog
    NUP153, nucleoporin 153
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NUP153, nucleoporin 153
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HNUP153, N153
  • Links
    NCBI Gene ID: 9972
    neXtProt AC: NX_P49790
    UniProt: P49790

  • Chr Location
    6p22.3; chr6:17615035-17706834 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 68442
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: NUP153
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 218210 NCBI Gene Model | MGI Sequence Detail 47948 C57BL/6J ±  kb
transcript NM_175749 RefSeq | MGI Sequence Detail 6021 C57BL/6  
polypeptide NP_786925 RefSeq | MGI Sequence Detail 1462 C57BL/6  
For the selected sequence
Protein
Information
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  • UniProt
    10 Sequences
  • InterPro Domains
    IPR026054 Nuclear pore complex protein
    IPR037625 Nuclear pore complex protein Nup153
    IPR013913 Nucleoporin Nup153, N-terminal
    IPR018892 Retro-transposon transporting motif
    IPR001876 Zinc finger, RanBP2-type
    IPR036443 Zinc finger, RanBP2-type superfamily
Molecular
Reagents
less
  • All nucleic 19
    cDNA 18
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:2145538, MGI:2443046
References
more
  • Summaries
    All 39
    Developmental Gene Expression 5
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:245014 Giacomini C, et al., Lamin B1 protein is required for dendrite development in primary mouse cortical neurons. Mol Biol Cell. 2016 Jan 01;27(1):35-47

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory