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Lrfn4 Gene Detail
Summary
  • Symbol
    Lrfn4
  • Name
    leucine rich repeat and fibronectin type III domain containing 4
  • Synonyms
    MGC:36464, MGC:36545, SALM3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385612
    NCBI Gene: 225875
Location & Maps
more
Homology
more
  • Human Ortholog
    LRFN4, leucine rich repeat and fibronectin type III domain containing 4
  • Vertebrate Orthologs
    9
  • Human Ortholog
    LRFN4, leucine rich repeat and fibronectin type III domain containing 4
    Orthology source: HomoloGene
  • Synonyms
    FIGLER6, SALM3, SALM3.
  • Links
    NCBI Gene ID: 78999
    neXtProt AC: NX_Q6PJG9

  • Chr Location
    11q13.2; chr11:66856480-66860475 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    4
  • Gene trapped
    1
  • Targeted
    3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014906 VEGA Gene Model | MGI Sequence Detail 3883 C57BL/6J ±  kb
transcript OTTMUST00000035411 VEGA | MGI Sequence Detail 2918 Not Applicable  
polypeptide OTTMUSP00000015831 VEGA | MGI Sequence Detail 636 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    3 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000029610 leucine-rich repeat and fibronectin type III domain-containing protein 4
  • InterPro Domains
    IPR000483 Cysteine-rich flanking region, C-terminal
    IPR003961 Fibronectin type III
    IPR013098 Immunoglobulin I-set
    IPR007110 Immunoglobulin-like domain
    IPR013783 Immunoglobulin-like fold
    IPR003598 Immunoglobulin subtype 2
    IPR001611 Leucine-rich repeat
    IPR032675 Leucine-rich repeat domain, L domain-like
    IPR000372 Leucine-rich repeat N-terminal domain
    IPR003591 Leucine-rich repeat, typical subtype
Molecular
Reagents
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  • All nucleic 51
    cDNA 49
    Primer pair 1
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:165063 Mah W, et al., Selected SALM (synaptic adhesion-like molecule) family proteins regulate synapse formation. J Neurosci. 2010 Apr 21;30(16):5559-68

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory