Lrfn4
Gene Detail

Symbol Name ID

Lrfn4 leucine rich repeat and fibronectin type III domain containing 4 MGI:2385612

Synonyms

MGC:36464, MGC:36545, SALM3

Feature Type

protein coding gene

Genetic Map

Chromosome 19

4.07 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr19:4611785-4615667 bp, - strand From VEGA annotation of GRCm38   3883 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:36415  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Lrfn4

Human homologs

Human Homolog		LRFN4, leucine rich repeat and fibronectin type III domain containing 4
NCBI Gene ID		78999
neXtProt AC		NX_Q6PJG9
Human Synonyms		FIGLER6, SALM3, SALM3.
Human Chr (Location)		11q13.2; chr11:66624876-66627946 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(4) : Targeted(3) Gene trapped(1)

Gene Ontology (GO) classifications

All GO classifications: (2 annotations)

Component

integral to membrane, membrane

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (77)    Tissues (64)    Images (8)
Theiler Stages: 6, 8, 9, 11, 13, 15, 17, 19, 20, 21, 22, 23, 24, 25, 26, 28

Assay Type	Results
RNA in situ	42
Northern blot	35

cDNA source data(48)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(50) cDNA(48) Primer pair(1) Other(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000014906 (Evidence)
Ensembl Gene Model	ENSMUSG00000045045 (Evidence)
Entrez Gene	225875 (Evidence)
UniGene	329675
DFCI	TC1578947, TC1593240, TC1601859
DoTS	DT.101380799, DT.40183462
NIA Mouse Gene Index	U019079
Consensus CDS Project	CCDS29431.1
International Mouse Knockout Project Status	Lrfn4

Sequences

Length	Strain/Species
genomic	OTTMUSG00000014906	VEGA Gene Model | MGI Sequence Detail	3883	C57BL/6J
transcript	OTTMUST00000035412	VEGA | MGI Sequence Detail	3194	Not Applicable
polypeptide	OTTMUSP00000015832	VEGA | MGI Sequence Detail	636	Not Applicable

All sequences(35) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(1 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000483	Cysteine-rich flanking region, C-terminal
InterPro	IPR003961	Fibronectin, type III
InterPro	IPR013098	Immunoglobulin I-set
InterPro	IPR007110	Immunoglobulin-like
InterPro	IPR013783	Immunoglobulin-like fold
InterPro	IPR003598	Immunoglobulin subtype 2
InterPro	IPR001611	Leucine-rich repeat
InterPro	IPR000372	Leucine-rich repeat-containing N-terminal
InterPro	IPR003591	Leucine-rich repeat, typical subtype
Protein Ontology	PR:000029610	leucine-rich repeat and fibronectin type-III domain-containing protein 4

References

(Earliest) J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
(Latest) J:165063 Mah W, et al., Selected SALM (synaptic adhesion-like molecule) family proteins regulate synapse formation. J Neurosci. 2010 Apr 21;30(16):5559-68
All references(32)