Uroc1
Gene Detail

Symbol Name ID

Uroc1 urocanase domain containing 1 MGI:2385332

Synonyms

MGC:37818

Feature Type

protein coding gene

Genetic Map

Chromosome 6

40.15 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr6:90333289-90364551 bp, + strand From VEGA annotation of GRCm38   31263 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:76629  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: urocanate hydratase
Gene Tree: Uroc1

Human homologs

Human Homolog		UROC1, urocanate hydratase 1
NCBI Gene ID		131669
neXtProt AC		NX_Q96N76
Human Synonyms		HMFN0320
Human Chr (Location)		3q21.3; chr3:126200008-126236616 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human UROC1

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (5 annotations)

Process	histidine catabolic process, histidine metabolic process
Component	cytosol
Function	lyase activity, urocanate hydratase activity

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (117)    Tissues (94)    Images (25)
Theiler Stages: 22, 23

Assay Type	Results
RNA in situ	117

cDNA source data(16)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(16) cDNA(16)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000036118 (Evidence)
Ensembl Gene Model	ENSMUSG00000034456 (Evidence)
Entrez Gene	243537 (Evidence)
UniGene	335669
DFCI	TC1585213
DoTS	DT.55163562, DT.91346414
NIA Mouse Gene Index	U007171
EC	4.2.1.49
Consensus CDS Project	CCDS39561.1
International Mouse Knockout Project Status	Uroc1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000036118	VEGA Gene Model | MGI Sequence Detail	31263	C57BL/6J
transcript	OTTMUST00000092830	VEGA | MGI Sequence Detail	3462	Not Applicable
polypeptide	OTTMUSP00000051375	VEGA | MGI Sequence Detail	710	Not Applicable

All sequences(23) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(293 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000193	Urocanase
InterPro	IPR023636	Urocanase conserved site
InterPro	IPR023637	Urocanase domain
Protein Ontology	PR:000031440	urocanate hydratase

References

(Earliest) J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(29)

Other accession IDs

MGI:2141387