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Stard13 Gene Detail
Summary
  • Symbol
    Stard13
  • Name
    StAR-related lipid transfer (START) domain containing 13
  • Synonyms
    DLC2, GT650, MGC:38133
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385331
    NCBI Gene: 243362
  • Gene Overview
    MyGene.info: STARD13
  • Alliance
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:151037510-151233836 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 89.82 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    3121 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385331
protein coding gene Chr5:151037510-151428261 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030415
protein coding gene Chr5:157019599-157235500 (-)
A/J MGP_AJ_G0030388
protein coding gene Chr5:150288797-150484956 (-)
AKR/J MGP_AKRJ_G0030315
protein coding gene Chr5:154935127-155134153 (-)
BALB/cJ MGP_BALBcJ_G0030397
protein coding gene Chr5:151546228-151743823 (-)
C3H/HeJ MGP_C3HHeJ_G0030111
protein coding gene Chr5:155931259-156130330 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030852
protein coding gene Chr5:162733114-162940133 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028065
protein coding gene Chr5:144604674-144805318 (-)
CAST/EiJ MGP_CASTEiJ_G0029513
protein coding gene Chr5:155613625-155827287 (-)
CBA/J MGP_CBAJ_G0030089
protein coding gene Chr5:169606091-169821413 (-)
DBA/2J MGP_DBA2J_G0030233
protein coding gene Chr5:149929451-150126309 (-)
FVB/NJ MGP_FVBNJ_G0030187
protein coding gene Chr5:149177523-149374807 (-)
LP/J MGP_LPJ_G0030320
protein coding gene Chr5:157666886-157876414 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030223
protein coding gene Chr5:171626754-171834702 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030882
protein coding gene Chr5:154883345-155086653 (-)
PWK/PhJ MGP_PWKPhJ_G0029227
protein coding gene Chr5:149115370-149312159 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029063
protein coding gene Chr5:152178232-152384213 (-)
WSB/EiJ MGP_WSBEiJ_G0029590
protein coding gene Chr5:155696557-155901508 (-)



Homology
more
  • Human Ortholog
    STARD13, StAR related lipid transfer domain containing 13
  • Vertebrate Orthologs
    11
  • Human Ortholog
    STARD13, StAR related lipid transfer domain containing 13
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ARHGAP37, DLC2, GT650, LINC00464
  • Links
    NCBI Gene ID: 90627
    neXtProt AC: NX_Q9Y3M8
    UniProt: Q9Y3M8

  • Chr Location
    13q13.1-q13.2; chr13:33103135-33676835 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    18 phenotypes from 4 alleles in 6 genetic backgrounds
    1 images
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit small body size, decreased weight, and reduced adipose tissue. Mice homozygous for another knock-out allele exhibit increased angiogenesis in matrigel plugs and implanted tumors.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000016128 Ensembl Gene Model | MGI Sequence Detail 196327 C57BL/6J ±  kb
transcript ENSMUST00000062015 Ensembl | MGI Sequence Detail 5526 Not Applicable  
polypeptide ENSMUSP00000053232 Ensembl | MGI Sequence Detail 1132 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    6 Sequences
  • InterPro Domains
    IPR000198 Rho GTPase-activating protein domain
    IPR008936 Rho GTPase activation protein
    IPR002913 START domain
    IPR023393 START-like domain superfamily
    IPR001660 Sterile alpha motif domain
    IPR013761 Sterile alpha motif/pointed domain superfamily
Molecular
Reagents
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  • All nucleic 24
    cDNA 24

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:225710 Tuck E, et al., A gene expression resource generated by genome-wide lacZ profiling in the mouse. Dis Model Mech. 2015 Nov 1;8(11):1467-78

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory