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BC021891 Gene Detail
Summary
  • Symbol
    BC021891
  • Name
    cDNA sequence BC021891
  • Synonyms
    MGC:27778
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385307
    NCBI Gene: 234878
Location & Maps
more
  • Sequence Map
    Chr8:125910450-125947439 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      36990 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 73.65 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    KIAA1804, mixed lineage kinase 4
  • Vertebrate Orthologs
    9
  • Human Ortholog
    KIAA1804, mixed lineage kinase 4
    Orthology source: HomoloGene
  • Synonyms
    dJ862P8.3, MLK4
  • Links
    NCBI Gene ID: 84451
    neXtProt AC: NX_Q5TCX8

  • Chr Location
    1q42; chr1:233327743-233385148 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031853 Ensembl Gene Model | MGI Sequence Detail 36990 C57BL/6J ±  kb
transcript ENSMUST00000034316 Ensembl | MGI Sequence Detail 5692 Not Applicable  
polypeptide ENSMUSP00000034316 Ensembl | MGI Sequence Detail 1002 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    219 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000010444 mitogen-activated protein kinase kinase kinase
  • EC
  • InterPro Domains
    IPR016231 Mitogen-activated protein (MAP) kinase kinase kinase, MLK1/MLK2/MLK4
    IPR017441 Protein kinase, ATP binding site
    IPR000719 Protein kinase domain
    IPR011009 Protein kinase-like domain
    IPR008271 Serine/threonine-protein kinase, active site
    IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
    IPR001452 SH3 domain
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 3
References
more
  • Summaries
    All 20
    Gene Ontology 3
    Phenotypes 1
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory