About   Help   FAQ
Ctu1 Gene Detail
Summary
  • Symbol
    Ctu1
  • Name
    cytosolic thiouridylase subunit 1
  • Synonyms
    Atpbd3, MGC:6894
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385277
    NCBI Gene: 233189
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:43321440-43327722 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 28.26 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    80 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385277
 protein coding gene Chr7:43321400-43327724 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032136
 protein coding gene Chr7:43700206-43706459 (+)
A/J MGP_AJ_G0032121
 protein coding gene Chr7:42800398-42806680 (+)
AKR/J MGP_AKRJ_G0032051
 protein coding gene Chr7:44179722-44187803 (+)
BALB/cJ MGP_BALBcJ_G0032126
 protein coding gene Chr7:42916879-42923112 (+)
C3H/HeJ MGP_C3HHeJ_G0031842
 protein coding gene Chr7:44681905-44688180 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032610
 protein coding gene Chr7:45900482-45906764 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029633
 protein coding gene Chr7:44931264-44938696 (+)
CAST/EiJ MGP_CASTEiJ_G0031172
 protein coding gene Chr7:35864004-35870270 (+)
CBA/J MGP_CBAJ_G0031811
 protein coding gene Chr7:47356098-47362502 (+)
DBA/2J MGP_DBA2J_G0031960
 protein coding gene Chr7:42607202-42613487 (+)
FVB/NJ MGP_FVBNJ_G0031921
 protein coding gene Chr7:42319059-42325808 (+)
LP/J MGP_LPJ_G0032039
 protein coding gene Chr7:44433966-44440245 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031957
 protein coding gene Chr7:46288840-46295297 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032630
 protein coding gene Chr7:43307676-43313988 (+)
PWK/PhJ MGP_PWKPhJ_G0030893
 protein coding gene Chr7:36049344-36058532 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030732
 protein coding gene Chr7:31351057-31356529 (+)
WSB/EiJ MGP_WSBEiJ_G0031286
 protein coding gene Chr7:43849971-43856184 (+)



Homology
more
  • Human Ortholog
    CTU1, cytosolic thiouridylase subunit 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CTU1, cytosolic thiouridylase subunit 1
  • Synonyms
    ATPBD3, NCS6
  • Links
    NCBI Gene ID: 90353
    neXtProt AC: NX_Q7Z7A3
    UniProt: Q7Z7A3

  • Chr Location
    19q13.41; chr19:51097606-51108409 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    707
  • Tissues
    1
  • cDNA Data
    21
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038888 Ensembl Gene Model | MGI Sequence Detail 6283 C57BL/6J ±  kb
transcript ENSMUST00000038332 Ensembl | MGI Sequence Detail 2475 Not Applicable  
polypeptide ENSMUSP00000036770 Ensembl | MGI Sequence Detail 420 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000004497 cytoplasmic tRNA 2-thiolation protein 1
    (term hierarchy)
  • EC
    2.7.7.-
  • InterPro Domains
    IPR000541 Cytoplasmic tRNA 2-thiolation protein 1
    IPR032442 Cytoplasmic tRNA 2-thiolation protein 1, C-terminal
    IPR014729 Rossmann-like alpha/beta/alpha sandwich fold
    IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal
Molecular
Reagents
less
  • All nucleic 21
    cDNA 21

    Microarray probesets 2
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:310882 Urbanek ME, et al., Genetic predisposition to tinnitus in the UK Biobank population. Sci Rep. 2021 Sep 13;11(1):18150
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory