Tmprss11d
Gene Detail

Symbol Name ID

Tmprss11d transmembrane protease, serine 11d MGI:2385221

Synonyms

AsP, MGC:28382

Feature Type

protein coding gene

Genetic Map

Chromosome 5

43.56 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr5:86302217-86373420 bp, - strand From VEGA annotation of GRCm38   71204 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:128622  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: transmembrane serine protease, TMPRSS11A type
Gene Tree: Tmprss11d

Human homologs

Human Homolog		TMPRSS11D, transmembrane protease, serine 11D
NCBI Gene ID		9407
neXtProt AC		NX_O60235
Human Synonyms		HAT
Human Chr (Location)		4q13.2; chr4:68686594-68749716 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(3) : Targeted(1) Gene trapped(2)

Gene Ontology (GO) classifications

All GO classifications: (15 annotations)

Process	proteolysis, regulation of growth
Component	cell surface, extracellular region, ...
Function	catalytic activity, hydrolase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (24)    Tissues (11)    Images (10)
Theiler Stages: 15, 19, 21, 23, 25, 28

Assay Type	Results
RNA in situ	17
RT-PCR	7

cDNA source data(1)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(2) cDNA(1) Primer pair(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000028240 (Evidence)
Ensembl Gene Model	ENSMUSG00000061259 (Evidence)
Entrez Gene	231382 (Evidence)
UniGene	240139
DFCI	TC1589260
DoTS	DT.101712268, DT.91351174
NIA Mouse Gene Index	U026347
EC	3.4.21.-
PDB	2E7V
Consensus CDS Project	CCDS39124.1
International Mouse Knockout Project Status	Tmprss11d

Sequences

Length	Strain/Species
genomic	OTTMUSG00000028240	VEGA Gene Model | MGI Sequence Detail	71204	C57BL/6J
transcript	OTTMUST00000069973	VEGA | MGI Sequence Detail	2716	Not Applicable
polypeptide	OTTMUSP00000035603	VEGA | MGI Sequence Detail	417	Not Applicable

All sequences(23) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(365 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR009003	Peptidase cysteine/serine, trypsin-like
InterPro	IPR001314	Peptidase S1A, chymotrypsin-type
InterPro	IPR017329	Peptidase S1A, HAT/DESC1
InterPro	IPR001254	Peptidase S1/S6, chymotrypsin/Hap
InterPro	IPR018114	Peptidase S1/S6, chymotrypsin/Hap, active site
InterPro	IPR000082	SEA
Protein Ontology	PR:000016450	transmembrane protease serine 11D

References

(Earliest) J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
(Latest) J:175364 Sales KU, et al., Expression and Genetic Loss of Function Analysis of the HAT/DESC Cluster Proteases TMPRSS11A and HAT. PLoS One. 2011;6(8):e23261
All references(28)