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Tmprss11d Gene Detail
Summary
  • Symbol
    Tmprss11d
  • Name
    transmembrane protease, serine 11d
  • Synonyms
    AsP, MGC:28382
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385221
    NCBI Gene: 231382
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:86450713-86521246 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 43.56 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1713 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385221
 protein coding gene Chr5:86450076-86521279 (-)
129S1/SvImJ ENSMUSG00200008169
 protein coding gene Chr5:82181138-82252358 (-)
A/J ENSMUSG00195024018
 protein coding gene Chr5:81351235-81422446 (-)
AKR/J ENSMUSG00220011191
 protein coding gene Chr5:81485202-81556411 (-)
BALB/cJ ENSMUSG00180000059
 protein coding gene Chr5:81201694-81266207 (-)
C3H/HeJ ENSMUSG00175042072
 protein coding gene Chr5:83279830-83344340 (-)
C57BL/6NJ ENSMUSG00215029936
 protein coding gene Chr5:82044347-82115557 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027341
 protein coding gene Chr5:79411371-79476372 (-)
CAST/EiJ ENSTCUG00005031565
 protein coding gene Chr5:80846606-80917608 (-)
CBA/J ENSMUSG00210004844
 protein coding gene Chr5:82093490-82163195 (-)
DBA/2J ENSMUSG00185039740
 protein coding gene Chr5:84017811-84082321 (-)
FVB/NJ ENSMUSG00205001133
 protein coding gene Chr5:80893805-80959523 (-)
JF1/MsJ ENSUMUG00000000653
 protein coding gene Chr5:88402773-88467210 (-)
LP/J ENSMUSG00230001052
 protein coding gene Chr5:88718210-88789409 (-)
NOD/ShiLtJ ENSMUSG00190033665
 protein coding gene Chr5:80960039-81024542 (-)
NZO/HlLtJ ENSMUSG00225008013
 protein coding gene Chr5:93742169-93813354 (-)
PWK/PhJ ENSLUMG00010025633
 protein coding gene Chr5:80889386-80953808 (-)
SPRET/EiJ ENSMSPG00010028655
 protein coding gene Chr5:83120638-83177068 (-)
WSB/EiJ ENSIUOG00005027191
 protein coding gene Chr5:83906051-83971150 (-)



Homology
more
  • Human Ortholog
    TMPRSS11D, transmembrane serine protease 11D
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMPRSS11D, transmembrane serine protease 11D
  • Synonyms
    ASP, HAT
  • Links
    NCBI Gene ID: 9407
    UniProt: O60235

  • Chr Location
    4q13.2; chr4:67820876-67884002 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from multigenic genotypes
    11 phenotype references
Aged female mice homozygous for a knock-in allele exhibit increased lymphoma incidence.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    621
  • Tissues
    11
  • cDNA Data
    2
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 231382 NCBI Gene Model | MGI Sequence Detail 70534 C57BL/6J ±  kb
transcript NM_145561 RefSeq | MGI Sequence Detail 2046 C57BL/6  
polypeptide Q8VHK8 UniProt | EBI | MGI Sequence Detail 417 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 2
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 11
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:279596 Callies LK, et al., Iterative, multiplexed CRISPR-mediated gene editing for functional analysis of complex protease gene clusters. J Biol Chem. 2019 Sep 9;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory