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Gnl2 Gene Detail
Summary
  • Symbol
    Gnl2
  • Name
    guanine nucleotide binding protein-like 2 (nucleolar)
  • Synonyms
    MGC:7863, Ngp-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385207
    NCBI Gene: 230737
  • Gene Overview
    MyGene.info: GNL2
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:125029989-125055382 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 57.97 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    111 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385207
protein coding gene Chr4:125016585-125055382 (.)
129S1/SvImJ MGP_129S1SvImJ_G0028761
protein coding gene Chr4:126593256-126635455 (+)
A/J MGP_AJ_G0028720
protein coding gene Chr4:121617158-121656773 (+)
AKR/J MGP_AKRJ_G0028673
protein coding gene Chr4:124957269-124996946 (+)
BALB/cJ MGP_BALBcJ_G0028743
protein coding gene Chr4:122199779-122249115 (+)
C3H/HeJ MGP_C3HHeJ_G0028457
protein coding gene Chr4:125031176-125072900 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029185
protein coding gene Chr4:131455157-131498379 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026458
protein coding gene Chr4:114787041-114826328 (+)
CAST/EiJ MGP_CASTEiJ_G0027890
protein coding gene Chr4:123104952-123147594 (+)
CBA/J MGP_CBAJ_G0028423
protein coding gene Chr4:134737692-134780390 (+)
DBA/2J MGP_DBA2J_G0028572
protein coding gene Chr4:122090329-122130167 (+)
FVB/NJ MGP_FVBNJ_G0028539
protein coding gene Chr4:120720362-120758879 (+)
LP/J MGP_LPJ_G0028673
protein coding gene Chr4:126879267-126920949 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028565
protein coding gene Chr4:139712870-139755485 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029223
protein coding gene Chr4:125307456-125348499 (+)
PWK/PhJ MGP_PWKPhJ_G0027611
protein coding gene Chr4:118520890-118561573 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027437
protein coding gene Chr4:121081751-121126232 (+)
WSB/EiJ MGP_WSBEiJ_G0027970
protein coding gene Chr4:125386904-125429504 (+)



Homology
more
  • Human Ortholog
    GNL2, G protein nucleolar 2
  • Vertebrate Orthologs
    11
  • Human Ortholog
    GNL2, G protein nucleolar 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HUMAUANTIG, Ngp-1, NGP1, Nog2, Nug2
  • Links
    NCBI Gene ID: 29889
    neXtProt AC: NX_Q13823
    UniProt: Q13823

  • Chr Location
    1p34.3; chr1:37566812-37595985 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 6858
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;2 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: GNL2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 230737 NCBI Gene Model | MGI Sequence Detail 25394 C57BL/6J ±  kb
transcript NM_145552 RefSeq | MGI Sequence Detail 2350 C57BL/6  
polypeptide Q99LH1 UniProt | EBI | MGI Sequence Detail 728 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000008116 nucleolar GTP-binding protein 2
  • InterPro Domains
    IPR030378 Circularly permuted (CP)-type guanine nucleotide-binding (G) domain
    IPR006073 GTP binding domain
    IPR023179 GTP-binding protein, orthogonal bundle domain superfamily
    IPR024929 Nucleolar GTP-binding protein 2
    IPR012971 Nucleolar GTP-binding protein 2, N-terminal domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less
  • All nucleic 107
    cDNA 107

    Microarray probesets 5
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory