About   Help   FAQ
Pabpc4
Gene Detail
Symbol

Name
ID
Pabpc4
poly(A) binding protein, cytoplasmic 4
MGI:2385206
Synonyms
MGC:11665, MGC:6685
Feature Type
protein coding gene
Genetic Map
Chromosome 4
57.42 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:123262351-123298925 bp, + strand
From VEGA annotation of GRCm38

  36575 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37855  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Pabpc4

Human
homologs
Human Homolog PABPC4, poly(A) binding protein, cytoplasmic 4 (inducible form)
NCBI Gene ID 8761
neXtProt AC  NX_Q13310
Human Synonyms  APP1, APP-1, iPABP, PABP4
Human Chr (Location)  1p34.2; chr1:39560813-39576849 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(17) : Gene trapped(15) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Pabpc4 interacts with 70 markers (Mir1b, Mir10a, Mir15a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process biological_process
Component cytoplasm, cytoplasmic stress granule, ...
Function poly(A) binding, poly(A) RNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (23)    Tissues (23)    Images (5)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 21
RT-PCR 2
cDNA source data(11)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) Genomic(1) cDNA(11) Primer pair(1)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000008978 (Evidence)
Ensembl Gene ModelENSMUSG00000011257 (Evidence)
Entrez Gene230721 (Evidence)
DFCITC1572831, TC1649567
Consensus CDS ProjectCCDS18614.1, CCDS18615.1
International Mouse Knockout Project StatusPabpc4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008978 VEGA Gene Model | MGI Sequence Detail 36575 C57BL/6J ±  kb
transcript OTTMUST00000020376 VEGA | MGI Sequence Detail 3019 Not Applicable 
polypeptide OTTMUSP00000009342 VEGA | MGI Sequence Detail 660 Not Applicable 

For the selected sequences
All sequences(68) RefSeq(14) UniProt(9)
Polymorphisms
SNPs within 2kb(142 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012677 Nucleotide-binding, alpha-beta plait
InterPro IPR006515 Polyadenylate binding protein, human types 1, 2, 3, 4
InterPro IPR002004 Polyadenylate-binding protein/Hyperplastic disc protein
InterPro IPR000504 RNA recognition motif domain
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:201630 Ryder E, et al., Molecular characterization of mutant mouse strains generated from the EUCOMM/KOMP-CSD ES cell resource. Mamm Genome. 2013 Aug;24(7-8):286-94
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2014
MGI 5.20
The Jackson Laboratory