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Efcab7 Gene Detail
Summary
  • Symbol
    Efcab7
  • Name
    EF-hand calcium binding domain 7
  • Synonyms
    MGC:28352
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385199
    NCBI Gene: 230500
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:99829500-99912785 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 45.71 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    351 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385199
protein coding gene Chr4:99829198-99912788 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028484
protein coding gene Chr4:100096567-100153805 (+)
A/J MGP_AJ_G0028447
protein coding gene Chr4:96601183-96654549 (+)
AKR/J MGP_AKRJ_G0028394
protein coding gene Chr4:98941341-98998454 (+)
BALB/cJ MGP_BALBcJ_G0028465
protein coding gene Chr4:96852289-96906214 (+)
C3H/HeJ MGP_C3HHeJ_G0028178
protein coding gene Chr4:99769537-99822651 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028904
protein coding gene Chr4:103898651-103955126 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026196
protein coding gene Chr4:91971358-92023103 (+)
CAST/EiJ MGP_CASTEiJ_G0027618
protein coding gene Chr4:97550234-97603408 (+)
CBA/J MGP_CBAJ_G0028147
protein coding gene Chr4:107095874-107189106 (+)
DBA/2J MGP_DBA2J_G0028297
protein coding gene Chr4:96320036-96375368 (+)
FVB/NJ MGP_FVBNJ_G0028264
protein coding gene Chr4:95167142-95221724 (+)
LP/J MGP_LPJ_G0028397
protein coding gene Chr4:100399917-100463630 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028292
protein coding gene Chr4:112776484-112825794 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028942
protein coding gene Chr4:99192129-99248812 (+)
PWK/PhJ MGP_PWKPhJ_G0027343
protein coding gene Chr4:94479516-94531858 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027165
protein coding gene Chr4:96642669-96702747 (+)
WSB/EiJ MGP_WSBEiJ_G0027696
protein coding gene Chr4:99353324-99415184 (+)



Homology
more
  • Human Ortholog
    EFCAB7, EF-hand calcium binding domain 7
  • Vertebrate Orthologs
    10
  • Human Ortholog
    EFCAB7, EF-hand calcium binding domain 7
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 84455
    neXtProt AC: NX_A8K855
    UniProt: A8K855

  • Chr Location
    1p31.3; chr1:63523301-63585400 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 19952
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: EFCAB7
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
  • UniProt
  • UniGene
Representative SequencesLengthStrain/SpeciesFlank
genomic 230500 NCBI Gene Model | MGI Sequence Detail 83286 C57BL/6J ±  kb
transcript NM_145549 RefSeq | MGI Sequence Detail 2132 CZECHII  
polypeptide Q8VDY4 UniProt | EBI | MGI Sequence Detail 628 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 15
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:243385 Pusapati GV, et al., EFCAB7 and IQCE regulate hedgehog signaling by tethering the EVC-EVC2 complex to the base of primary cilia. Dev Cell. 2014 Mar 10;28(5):483-96

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/04/2019
MGI 6.14
The Jackson Laboratory