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Rap1gds1 Gene Detail
Summary
  • Symbol
    Rap1gds1
  • Name
    RAP1, GTP-GDP dissociation stimulator 1
  • Synonyms
    GDS1, MGC:18981
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385189
    NCBI Gene: 229877
  • Gene Overview
    MyGene.info: RAP1GDS1
Location & Maps
more
  • Sequence Map
    Chr3:138925902-139075201 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      149300 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 64.52 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    RAP1GDS1, Rap1 GTPase-GDP dissociation stimulator 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RAP1GDS1, Rap1 GTPase-GDP dissociation stimulator 1
    Orthology source: HomoloGene
  • Synonyms
    GDS1, SmgGDS
  • Links
    NCBI Gene ID: 5910
    neXtProt AC: NX_P52306

  • Chr Location
    4q23; chr4:98261376-98443861 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    39
  • Chemically induced (other)
    1
  • Gene trapped
    36
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Rap1gds1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000052979 VEGA Gene Model | MGI Sequence Detail 149300 C57BL/6J ±  kb
transcript OTTMUST00000132552 VEGA | MGI Sequence Detail 3669 Not Applicable  
polypeptide OTTMUSP00000070666 VEGA | MGI Sequence Detail 607 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1485 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 131
    cDNA 131

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:226036 Maddala R, et al., Rap1 GTPase is required for mouse lens epithelial maintenance and morphogenesis. Dev Biol. 2015 Oct 1;406(1):74-91

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory