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Ahcyl1
Gene Detail
Symbol

Name
ID
Ahcyl1
S-adenosylhomocysteine hydrolase-like 1
MGI:2385184
Synonyms
1110034F20Rik, Ahcy-rs3, DCAL, IRBIT
Feature Type
protein coding gene
Genetic Map
Chromosome 3
46.83 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr3:107663118-107696560 bp, - strand
From VEGA annotation of GRCm38

  33443 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:77353  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: adenosylhomocysteine hydrolase, SAHH type
Gene Tree: Ahcyl1

Human
homologs
Human Homolog AHCYL1, adenosylhomocysteinase-like 1
NCBI Gene ID 10768
neXtProt AC  NX_O43865
Human Synonyms  DCAL, IRBIT, PPP1R78, PRO0233, XPVKONA
Human Chr (Location)  1p13.2; chr1:109984765-110023742 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(3) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ahcyl1 interacts with 354 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process mRNA polyadenylation, one-carbon metabolic process, ...
Component cell, endoplasmic reticulum, ...
Function adenosylhomocysteinase activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Images (13)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(184)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(186) cDNA(184) Primer pair(2)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000029454 (Evidence)
Ensembl Gene ModelENSMUSG00000027893 (Evidence)
Entrez Gene229709 (Evidence)
UniGene220328
DFCITC1576594, TC1622547, TC1712293
DoTSDT.40177199, DT.91481630, DT.97335610
NIA Mouse Gene IndexU024501
EC3.3.1.1
Consensus CDS ProjectCCDS38593.1
International Mouse Knockout Project StatusAhcyl1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029454 VEGA Gene Model | MGI Sequence Detail 33443 C57BL/6J ±  kb
transcript OTTMUST00000072984 VEGA | MGI Sequence Detail 3863 Not Applicable 
polypeptide OTTMUSP00000037720 VEGA | MGI Sequence Detail 530 Not Applicable 

For the selected sequences
All sequences(61) RefSeq(8) UniProt(3)
Polymorphisms
SNPs within 2kb(161 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000043 Adenosylhomocysteinase
InterPro IPR016040 NAD(P)-binding domain
InterPro IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site
InterPro IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain
Protein Ontology PR:000029742 adenosylhomocysteinase 2
References
(Earliest) J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
(Latest) J:180716 Martins JR, et al., F508del-CFTR increases intracellular Ca(2+) signaling that causes enhanced calcium-dependent Cl(-) conductance in cystic fibrosis. Biochim Biophys Acta. 2011 Nov;1812(11):1385-92
All references(45)
Other
accession IDs
MGD-MRK-36379, MGI:107802, MGI:1353558, MGI:1920996, MGI:2139575

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory