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Ahcyl1
Gene Detail
Symbol

Name
ID
Ahcyl1
S-adenosylhomocysteine hydrolase-like 1
MGI:2385184
Synonyms
1110034F20Rik, Ahcy-rs3, DCAL, IRBIT
Feature Type
protein coding gene
Genetic Map
Chromosome 3
46.83 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr3:107663118-107696560 bp, - strand
From VEGA annotation of GRCm38

  33443 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:77353  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: AHCYL1
Protein SuperFamily: adenosylhomocysteine hydrolase, SAHH type
Gene Tree: Ahcyl1

Human
homologs
AHCYL1, adenosylhomocysteinase-like 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 10768
neXtProt AC: NX_O43865

Human Synonyms: DCAL, IRBIT, PPP1R78, PRO0233, XPVKONA

Human Chr (Location): 1p13.2; chr1:109984741-110023742 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(3) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ahcyl1 interacts with 353 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (32 annotations)
Process angiotensin-activated signaling pathway, epithelial fluid transport, ...
Component apical plasma membrane, cytoplasm, ...
Function hydrolase activity, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Images (13)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(184)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA AHCYL1 ; Xenbase ahcyl1 ; ZFIN ahcyl1    NEW 
Molecular
reagents
All nucleic(186) cDNA(184) Primer pair(2)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000029454 (Evidence)
Ensembl Gene Model ENSMUSG00000027893 (Evidence)
Entrez Gene 229709 (Evidence)
UniGene 220328
DFCI TC1576594, TC1622547, TC1712293
DoTS DT.40177199, DT.91481630, DT.97335610
NIA Mouse Gene Index U024501
EC 3.3.1.1
Consensus CDS Project CCDS38593.1
International Mouse Phenotyping Consortium Status Ahcyl1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029454 VEGA Gene Model | MGI Sequence Detail 33443 C57BL/6J ±  kb
transcript OTTMUST00000072984 VEGA | MGI Sequence Detail 3863 Not Applicable 
polypeptide OTTMUSP00000037720 VEGA | MGI Sequence Detail 530 Not Applicable 

For the selected sequences
All sequences(57) RefSeq(4) UniProt(3)
Polymorphisms
SNPs within 2kb(161 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000043 Adenosylhomocysteinase
InterPro IPR016040 NAD(P)-binding domain
InterPro IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site
InterPro IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain
Protein Ontology PR:000029742 adenosylhomocysteinase 2
References
(Earliest) J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
(Latest) J:220505 Park S, et al., Irbit mediates synergy between ca(2+) and cAMP signaling pathways during epithelial transport in mice. Gastroenterology. 2013 Jul;145(1):232-41
All references(48)
Other
accession IDs
MGD-MRK-36379, MGI:107802, MGI:1353558, MGI:1920996, MGI:2139575

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory