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Tm4sf4 Gene Detail
Summary
  • Symbol
    Tm4sf4
  • Name
    transmembrane 4 superfamily member 4
  • Synonyms
    il-TMP, MGC:19127
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385173
    NCBI Gene: 229302
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:57425410-57441677 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 27.72 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    118 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385173
protein coding gene Chr3:57425314-57441677 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027228
protein coding gene Chr3:56214490-56232100 (+)
A/J MGP_AJ_G0027188
protein coding gene Chr3:54460404-54477126 (+)
AKR/J MGP_AKRJ_G0027158
protein coding gene Chr3:55598764-55615015 (+)
BALB/cJ MGP_BALBcJ_G0027201
protein coding gene Chr3:54301444-54315915 (+)
C3H/HeJ MGP_C3HHeJ_G0026944
protein coding gene Chr3:55792970-55807332 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027647
protein coding gene Chr3:58298556-58314854 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025005
protein coding gene Chr3:50865377-50881962 (+)
CAST/EiJ MGP_CASTEiJ_G0026396
protein coding gene Chr3:55947417-55965128 (+)
CBA/J MGP_CBAJ_G0026920
protein coding gene Chr3:60219746-60234713 (+)
DBA/2J MGP_DBA2J_G0027054
protein coding gene Chr3:53967192-53983725 (+)
FVB/NJ MGP_FVBNJ_G0027022
protein coding gene Chr3:52944810-52961142 (+)
LP/J MGP_LPJ_G0027166
protein coding gene Chr3:56947949-56965158 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027040
protein coding gene Chr3:64322630-64340389 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027705
protein coding gene Chr3:55532788-55549893 (+)
PWK/PhJ MGP_PWKPhJ_G0026128
protein coding gene Chr3:53618749-53634946 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025941
protein coding gene Chr3:55224901-55241176 (+)
WSB/EiJ MGP_WSBEiJ_G0026470
protein coding gene Chr3:55622454-55638701 (+)



Homology
more
  • Human Ortholog
    TM4SF4, transmembrane 4 L six family member 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TM4SF4, transmembrane 4 L six family member 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    il-TMP, ILTMP
  • Links
    NCBI Gene ID: 7104
    neXtProt AC: NX_P48230
    UniProt: P48230

  • Chr Location
    3q25.1; chr3:149474581-149503394 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 229302 NCBI Gene Model | MGI Sequence Detail 16268 C57BL/6J ±  kb
transcript NM_145539 RefSeq | MGI Sequence Detail 1417 C57BL/6  
polypeptide Q91XD3 UniProt | EBI | MGI Sequence Detail 202 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 23
    cDNA 23

    Microarray probesets 2
References
more
  • Summaries
    All 39
    Developmental Gene Expression 4
    Diseases 1
    Gene Ontology 2
    Phenotypes 13
  • Earliest
    J:64276 Lyon MF, et al., Dose-response curves for radiation-induced gene mutations in mouse oocytes and their interpretation. Mutat Res. 1979 Nov;63(1):161-73
  • Latest
    J:237787 Liu X, et al., Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA. BMC Immunol. 2016 Aug 02;17(1):25

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
01/07/2020
MGI 6.14
The Jackson Laboratory