Slc35c2 MGI Mouse Gene Detail - MGI:2385166 - solute carrier family 35, member C2

Symbol

Slc35c2
Name

solute carrier family 35, member C2
Synonyms

CGI-15, D2Wsu58e, MGC:18664, Ovcov1

Feature Type

protein coding gene
IDs

MGI:2385166
NCBI Gene: 228875
Gene Overview

MyGene.info: SLC35C2
Alliance

gene page
Transcription Start Sites

9 TSS

Sequence Map

Chr2:165276554-165287869 bp, - strand
From Ensembl annotation of GRCm38

View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 2, 85.53 cM
Mapping Data

3 experiments

SNPs within 2kb

109 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2385166	protein coding gene	Chr2:165276522-165287888 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0026889	protein coding gene	Chr2:170826068-170838518 (-)
A/J	MGP_AJ_G0026856	protein coding gene	Chr2:163824455-163838120 (-)
AKR/J	MGP_AKRJ_G0026827	protein coding gene	Chr2:168706383-168717706 (-)
BALB/cJ	MGP_BALBcJ_G0026865	protein coding gene	Chr2:164190376-164202209 (-)
C3H/HeJ	MGP_C3HHeJ_G0026607	protein coding gene	Chr2:169064960-169076983 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0027312	protein coding gene	Chr2:175769638-175780791 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0024683	protein coding gene	Chr2:157226751-157238059 (-)
CAST/EiJ	MGP_CASTEiJ_G0026065	protein coding gene	Chr2:169490664-169503850 (-)
CBA/J	MGP_CBAJ_G0026584	protein coding gene	Chr2:182166332-182177656 (-)
DBA/2J	MGP_DBA2J_G0026722	protein coding gene	Chr2:162985233-162996532 (-)
FVB/NJ	MGP_FVBNJ_G0026688	protein coding gene	Chr2:161427784-161439051 (-)
LP/J	MGP_LPJ_G0026824	protein coding gene	Chr2:170877382-170888666 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0026707	protein coding gene	Chr2:185677958-185689229 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0027369	protein coding gene	Chr2:168603785-168615109 (-)
PWK/PhJ	MGP_PWKPhJ_G0025802	protein coding gene	Chr2:162594843-162606400 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0025603	protein coding gene	Chr2:167519553-167530719 (-)
WSB/EiJ	MGP_WSBEiJ_G0026138	protein coding gene	Chr2:169500318-169511625 (-)

Human Ortholog

SLC35C2, solute carrier family 35 member C2

Vertebrate Orthologs

9

Human Ortholog

SLC35C2, solute carrier family 35 member C2
Orthology source: HomoloGene, HGNC
Synonyms

BA394O2.1, C20orf5, CGI-15, OVCOV1
Links

HGNC:17117

NCBI Gene ID: 51006

neXtProt AC: NX_Q9NQQ7

UniProt: Q9NQQ7
Chr Location

20q13.12; chr20:46349528-46364461 (-) GRCh38.p7

HomoloGene

Vertebrate Homology Class 6581
1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 macaque, rhesus
HCOP

human homology predictions: SLC35C2
Gene Tree

Slc35c2

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
7 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	immune system	integument	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	neoplasm	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	vision/eye

Click cells to view annotations.

All Mutations and Alleles

6
Gene trapped

3
Targeted

3
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

13 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

17
GO References

4

External Resources

FuncBase

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell death	cell differentiation	cell population proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	nucleic acid-templated transcription	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

148
Tissues

129
cDNA Data

14
Literature Summary

5

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase slc35c2

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Slc35c2 interacts with 204 markers (Mir1a-1, Mir1a-2, Mir7-1, ...) View All

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All Sequences

110
RefSeq

28
UniProt

11
CCDS

CCDS17074.1

Ensembl

ENSMUSG00000017664 (Evidence)
NCBI Gene

228875

			Length	Strain/Species	Flank
genomic	ENSMUSG00000017664	Ensembl Gene Model \| MGI Sequence Detail	11316	C57BL/6J	± kb
transcript	ENSMUST00000017808	Ensembl \| MGI Sequence Detail	1843	Not Applicable
polypeptide	ENSMUSP00000017808	Ensembl \| MGI Sequence Detail	364	Not Applicable

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UniProt

11 Sequences
Protein Ontology

PR:000015097 solute carrier family 35 member C2

(term hierarchy)
InterPro Domains

IPR004853 Sugar phosphate transporter domain

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All nucleic 16

cDNA 14

Primer pair 2

Microarray probesets 6

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MGD-MRK-34239, MGI:106545, MGI:2139522

Summaries

All 37

Developmental Gene Expression 5

Gene Ontology 4

Phenotypes 7
Earliest

J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
Latest

J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

TSS for Slc35c2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr27616	Chr2:165287853-165287863 (-)	11 bp
Tssr27615	Chr2:165287802-165287845 (-)	45 bp
Tssr27614	Chr2:165286913-165286933 (-)	946 bp
Tssr27613	Chr2:165286543-165286560 (-)	1,317 bp
Tssr27612	Chr2:165283768-165283789 (-)	4,090 bp
Tssr27611	Chr2:165283711-165283725 (-)	4,151 bp
Tssr27610	Chr2:165283656-165283683 (-)	4,199 bp
Tssr27609	Chr2:165283648-165283655 (-)	4,217 bp
Tssr27608	Chr2:165283599-165283620 (-)	4,259 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer & Copyright Notice Send questions and comments to User Support.	last database update 01/21/2020 MGI 6.14