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Sh3glb2 Gene Detail
Summary
  • Symbol
    Sh3glb2
  • Name
    SH3-domain GRB2-like endophilin B2
  • Synonyms
    mKIAA1848
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385131
    NCBI Gene: 227700
  • Gene Overview
    MyGene.info: SH3GLB2
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:30344809-30359337 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 21.60 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    43 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385131
protein coding gene Chr2:30344777-30359337 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025565
protein coding gene Chr2:28570243-28584715 (-)
A/J MGP_AJ_G0025543
protein coding gene Chr2:27430310-27444825 (-)
AKR/J MGP_AKRJ_G0025512
protein coding gene Chr2:28362022-28378284 (-)
BALB/cJ MGP_BALBcJ_G0025539
protein coding gene Chr2:27553709-27572269 (-)
C3H/HeJ MGP_C3HHeJ_G0025300
protein coding gene Chr2:28293956-28309228 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025984
protein coding gene Chr2:29506000-29520488 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023392
protein coding gene Chr2:26208259-26222931 (-)
CAST/EiJ MGP_CASTEiJ_G0024762
protein coding gene Chr2:28189768-28204267 (-)
CBA/J MGP_CBAJ_G0025277
protein coding gene Chr2:30509737-30524222 (-)
DBA/2J MGP_DBA2J_G0025410
protein coding gene Chr2:27219020-27234030 (-)
FVB/NJ MGP_FVBNJ_G0025373
protein coding gene Chr2:27038137-27053314 (-)
LP/J MGP_LPJ_G0025496
protein coding gene Chr2:28475726-28490067 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025403
protein coding gene Chr2:30389987-30407115 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026042
protein coding gene Chr2:28278636-28293116 (-)
PWK/PhJ MGP_PWKPhJ_G0024509
protein coding gene Chr2:27059382-27073877 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024309
protein coding gene Chr2:28395624-28410099 (-)
WSB/EiJ MGP_WSBEiJ_G0024830
protein coding gene Chr2:28405832-28420318 (-)



Homology
more
  • Human Ortholog
    SH3GLB2, SH3 domain containing GRB2 like, endophilin B2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SH3GLB2, SH3 domain containing GRB2 like, endophilin B2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PP6569, PP9455, RRIG1
  • Links
    NCBI Gene ID: 56904
    neXtProt AC: NX_Q9NR46
    UniProt: Q9NR46

  • Chr Location
    9q34.11; chr9:129007792-129028353 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026860 Ensembl Gene Model | MGI Sequence Detail 14529 C57BL/6J ±  kb
transcript ENSMUST00000113621 Ensembl | MGI Sequence Detail 1851 Not Applicable  
polypeptide ENSMUSP00000109251 Ensembl | MGI Sequence Detail 404 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 99
    cDNA 99

    Microarray probesets 3
References
more
  • Summaries
    All 26
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:86686 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Aug 31;10(4):167-80
  • Latest
    J:246421 Serfass JM, et al., Endophilin B2 facilitates endosome maturation in response to growth factor stimulation, autophagy induction, and influenza A virus infection. J Biol Chem. 2017 Jun 16;292(24):10097-10111

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory