About   Help   FAQ
Tkfc Gene Detail
Summary
  • Symbol
    Tkfc
  • Name
    triokinase, FMN cyclase
  • Synonyms
    Dak, MGC:28742
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385084
    NCBI Gene: 225913
  • Gene Overview
    MyGene.info: TKFC
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:10592200-10604258 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 6.60 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    66 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385084
protein coding gene Chr19:10592197-10605482 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024851
protein coding gene Chr19:7942160-7954218 (-)
A/J MGP_AJ_G0024819
protein coding gene Chr19:7403138-7415195 (-)
AKR/J MGP_AKRJ_G0024794
protein coding gene Chr19:7695750-7707807 (-)
BALB/cJ MGP_BALBcJ_G0024819
protein coding gene Chr19:7445995-7458052 (-)
C3H/HeJ MGP_C3HHeJ_G0024585
protein coding gene Chr19:7575693-7587750 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025267
protein coding gene Chr19:8301357-8314567 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022694
protein coding gene Chr19:7821001-7833905 (-)
CAST/EiJ MGP_CASTEiJ_G0024058
protein coding gene Chr19:7231374-7245909 (-)
CBA/J MGP_CBAJ_G0024559
protein coding gene Chr19:8345962-8358019 (-)
DBA/2J MGP_DBA2J_G0024686
protein coding gene Chr19:7412987-7425044 (-)
FVB/NJ MGP_FVBNJ_G0024653
protein coding gene Chr19:7457423-7471050 (-)
LP/J MGP_LPJ_G0024773
protein coding gene Chr19:7905563-7917621 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024680
protein coding gene Chr19:8249111-8261168 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025315
protein coding gene Chr19:7714175-7726233 (-)
PWK/PhJ MGP_PWKPhJ_G0023803
protein coding gene Chr19:6855672-6867804 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023608
protein coding gene Chr19:6891884-6904410 (-)
WSB/EiJ MGP_WSBEiJ_G0024120
protein coding gene Chr19:7598641-7611927 (-)



Homology
more
  • Human Ortholog
    TKFC, triokinase and FMN cyclase
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TKFC, triokinase and FMN cyclase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DAK, NET45
  • Links
    NCBI Gene ID: 26007
    neXtProt AC: NX_Q3LXA3
    UniProt: Q3LXA3

  • Chr Location
    11q12.2; chr11:61333182-61353426 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034371 Ensembl Gene Model | MGI Sequence Detail 12059 C57BL/6J ±  kb
transcript ENSMUST00000037678 Ensembl | MGI Sequence Detail 2253 Not Applicable  
polypeptide ENSMUSP00000044556 Ensembl | MGI Sequence Detail 578 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    cDNA 24

    Microarray probesets 2
References
more
  • Summaries
    All 28
    Gene Ontology 7
    Phenotypes 6
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:193640 Lo JC, et al., RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly. PLoS Genet. 2012;8(10):e1002969

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory