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Tkfc
Gene Detail
Symbol

Name
ID
Tkfc
triokinase, FMN cyclase
MGI:2385084
Synonyms
Dak, MGC:28742
Feature Type
protein coding gene
Genetic Map
Chromosome 19
6.60 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr19:10592200-10604258 bp, - strand
From Ensembl annotation of GRCm38

  12059 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56710  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Tkfc

Human
homologs
Human Homolog   TKFC, triokinase/FMN cyclase
NCBI Gene ID 26007
neXtProt AC  NX_Q3LXA3
Human Synonyms  DAK, NET45
Human Chr (Location)  11q12.2; chr11:61333182-61353139 (+)  GRCh38.p2
Mutations,
alleles, and
phenotypes
All mutations/alleles(17) : Gene trapped(16) Targeted(1)
Incidental mutations (data from APF , CvDC )
Interactions
Tkfc interacts with 52 markers (Mir7-1, Mir22, Mir26a-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process carbohydrate phosphorylation, cellular carbohydrate metabolic process, ...
Component extracellular exosome, nucleus
Function ATP binding, catalytic activity, ...
External Resources: FuncBase
Expression
cDNA source data(23)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(23) cDNA(23)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000034371 (Evidence)
Entrez Gene225913 (Evidence)
UniGene374868
DFCITC1586003
DoTSDT.40183212, DT.101281354, DT.97409557
NIA Mouse Gene IndexU038806
EC2.7.1.29, 4.6.1.15, 2.7.1.28
Consensus CDS ProjectCCDS37914.1
International Mouse Knockout Project StatusTkfc
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034371 Ensembl Gene Model | MGI Sequence Detail 12059 C57BL/6J ±  kb
transcript ENSMUST00000037678 Ensembl | MGI Sequence Detail 2253 Not Applicable 
polypeptide ENSMUSP00000044556 Ensembl | MGI Sequence Detail 578 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(12) UniProt(2)
Polymorphisms
SNPs within 2kb(63 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004006 Dak kinase
InterPro IPR004007 Dak phosphatase
InterPro IPR012734 Dihydroxyacetone kinase
Protein Ontology PR:000006270 bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)
References
(Earliest) J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
(Latest) J:193640 Lo JC, et al., RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly. PLoS Genet. 2012;8(10):e1002969
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/12/2015
MGI 5.21
The Jackson Laboratory