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Ndufs8
Gene Detail
Symbol

Name
ID
Ndufs8
NADH dehydrogenase (ubiquinone) Fe-S protein 8
MGI:2385079
Feature Type
protein coding gene
Genetic Map
Chromosome 19
3.63 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr19:3908870-3912717 bp, - strand
From Ensembl annotation of GRCm38

  3848 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1867  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Protein SuperFamily: NADH-ubiquinone oxidoreductase 23 kDa subunit
Gene Tree: Ndufs8

Human
homologs
Human Homolog NDUFS8, NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
NCBI Gene ID 4728
neXtProt AC  NX_O00217
Human Synonyms  CI-23k, CI23KD, TYKY
Human Chr (Location)  11q13; chr11:68030617-68036647 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human NDUFS8
Mutations,
alleles, and
phenotypes
All mutations/alleles(27) : Gene trapped(27)
Incidental mutations (data from APF )
Interactions
Ndufs8 interacts with 7 markers (Mir1b, Mir207, Mir376b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
cDNA source data(84)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(84) cDNA(84)
Microarray probesets(8)
Other database
links
Ensembl Gene ModelENSMUSG00000059734 (Evidence)
Entrez Gene225887 (Evidence)
UniGene44227
DFCITC1668055, TC1723687, TC1574384, TC1770163
DoTSDT.94192216, DT.94313318, DT.94192207, DT.99873261, DT.97390211
NIA Mouse Gene IndexU019109
EC1.6.99.3, 1.6.5.3
Consensus CDS ProjectCCDS29402.1
International Mouse Knockout Project StatusNdufs8
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000059734 Ensembl Gene Model | MGI Sequence Detail 3848 C57BL/6J ±  kb
transcript ENSMUST00000075092 Ensembl | MGI Sequence Detail 963 Not Applicable 
polypeptide ENSMUSP00000074600 Ensembl | MGI Sequence Detail 212 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(6) UniProt(7)
Polymorphisms
SNPs within 2kb(45 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001450 4Fe-4S binding domain
InterPro IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site
InterPro IPR017896 4Fe-4S ferredoxin-type, iron-sulpur binding domain
InterPro IPR010226 NADH-quinone oxidoreductase, chain I
Protein Ontology PR:000011103 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
References
(Earliest) J:50639 Schibler L, et al., Comparative gene mapping: a fine-scale survey of chromosome rearrangements between ruminants and humans. Genome Res. 1998 Sep;8(9):901-15
(Latest) J:172354 Wirtz S, et al., Region-Specific Expression of Mitochondrial Complex I Genes during Murine Brain Development. PLoS One. 2011;6(4):e18897
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory