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Ndufs8
Gene Detail
Symbol

Name
ID
Ndufs8
NADH dehydrogenase (ubiquinone) Fe-S protein 8
MGI:2385079
Feature Type
protein coding gene
Genetic Map
Chromosome 19
3.63 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr19:3908870-3912717 bp, - strand
From Ensembl annotation of GRCm38

  3848 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1867  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: NDUFS8
Protein SuperFamily: NADH-ubiquinone oxidoreductase 23 kDa subunit
Gene Tree: Ndufs8

Human
homologs
NDUFS8, NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 4728
neXtProt AC: NX_O00217

Human Synonyms: CI-23k, CI23KD, TYKY

Human Chr (Location): 11q13; chr11:68030617-68036647 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human NDUFS8

Mutations,
alleles, and
phenotypes
All mutations/alleles(27) : Gene trapped(27)
Incidental mutations (data from APF )
Interactions
Ndufs8 interacts with 7 markers (Mir1b, Mir207, Mir376b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
cDNA source data(84)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ndufs8 ; ZFIN ndufs8a, ndufs8b    NEW 
Molecular
reagents
All nucleic(84) cDNA(84)
Microarray probesets(8)
Other database
links
Ensembl Gene Model ENSMUSG00000059734 (Evidence)
Entrez Gene 225887 (Evidence)
UniGene 44227
DFCI TC1574384, TC1668055, TC1723687, TC1770163
DoTS DT.94192207, DT.94192216, DT.94313318, DT.97390211, DT.99873261
NIA Mouse Gene Index U019109
EC 1.6.5.3, 1.6.99.3
Consensus CDS Project CCDS29402.1
International Mouse Phenotyping Consortium Status Ndufs8
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000059734 Ensembl Gene Model | MGI Sequence Detail 3848 C57BL/6J ±  kb
transcript ENSMUST00000075092 Ensembl | MGI Sequence Detail 963 Not Applicable 
polypeptide ENSMUSP00000074600 Ensembl | MGI Sequence Detail 212 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(6) UniProt(4)
Polymorphisms
SNPs within 2kb(45 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site
InterPro IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain
InterPro IPR010226 NADH-quinone oxidoreductase, chain I
Protein Ontology PR:000011103 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
References
(Earliest) J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
(Latest) J:172354 Wirtz S, et al., Region-Specific Expression of Mitochondrial Complex I Genes during Murine Brain Development. PLoS One. 2011;6(4):e18897
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory