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Ndufs8 Gene Detail
Summary
  • Symbol
    Ndufs8
  • Name
    NADH:ubiquinone oxidoreductase core subunit S8
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385079
    NCBI Gene: 225887
  • Gene Overview
    MyGene.info: NDUFS8
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:3908870-3912717 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 3.63 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    45 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385079
protein coding gene Chr19:3908863-3912774 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024632
protein coding gene Chr19:717342-721189 (-)
A/J MGP_AJ_G0024599
protein coding gene Chr19:684387-688276 (-)
AKR/J MGP_AKRJ_G0024570
protein coding gene Chr19:693763-697610 (-)
BALB/cJ MGP_BALBcJ_G0024597
protein coding gene Chr19:694568-698415 (-)
C3H/HeJ MGP_C3HHeJ_G0024366
protein coding gene Chr19:694944-698836 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025045
protein coding gene Chr19:719453-723300 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022474
protein coding gene Chr19:650126-654034 (-)
CAST/EiJ MGP_CASTEiJ_G0023838
protein coding gene Chr19:708987-712815 (-)
CBA/J MGP_CBAJ_G0024336
protein coding gene Chr19:785777-789624 (-)
DBA/2J MGP_DBA2J_G0024465
protein coding gene Chr19:662100-665986 (-)
FVB/NJ MGP_FVBNJ_G0024432
protein coding gene Chr19:669904-675497 (-)
LP/J MGP_LPJ_G0024551
protein coding gene Chr19:710169-714016 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024462
protein coding gene Chr19:752138-756026 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025093
protein coding gene Chr19:700024-703835 (-)
PWK/PhJ MGP_PWKPhJ_G0023584
protein coding gene Chr19:686389-690230 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023391
protein coding gene Chr19:704781-711135 (-)
WSB/EiJ MGP_WSBEiJ_G0023901
protein coding gene Chr19:690933-694761 (-)



Homology
more
  • Human Ortholog
    NDUFS8, NADH:ubiquinone oxidoreductase core subunit S8
  • Vertebrate Orthologs
    11
  • Human Ortholog
    NDUFS8, NADH:ubiquinone oxidoreductase core subunit S8
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CI-23k, CI23KD, TYKY
  • Links
    NCBI Gene ID: 4728
    neXtProt AC: NX_O00217
    UniProt: O00217

  • Chr Location
    11q13.2; chr11:68030617-68036647 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human NDUFS8 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000059734 Ensembl Gene Model | MGI Sequence Detail 3848 C57BL/6J ±  kb
transcript ENSMUST00000075092 Ensembl | MGI Sequence Detail 963 Not Applicable  
polypeptide ENSMUSP00000074600 Ensembl | MGI Sequence Detail 212 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 85
    cDNA 85

    Microarray probesets 8
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 6
  • Earliest
    J:50639 Schibler L, et al., Comparative gene mapping: a fine-scale survey of chromosome rearrangements between ruminants and humans. Genome Res. 1998 Sep;8(9):901-15
  • Latest
    J:233841 Inoue M, et al., Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory