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Etf1
Gene Detail
 Symbol
Name
ID
Etf1
eukaryotic translation termination factor 1
MGI:2385071
Synonyms ERF1, MGC:18745, SUP45L1, TB3-1
Feature Type protein coding gene
Genetic Map
Chromosome 18
18.78 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr18:34902785-34932007 bp, - strand
From VEGA annotation of GRCm38

  29223 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3475  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: peptide chain release factor, subunit 1
Gene Tree: Etf1

Human
homologs
Human Homolog ETF1, eukaryotic translation termination factor 1
NCBI Gene ID 2107
neXtProt AC  NX_P62495
Human Synonyms  D5S1995, ERF, ERF1, RF1, SUP45L1, TB3-1
Human Chr (Location)  5q31.1; chr5:138506093-138543300 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(82) : Gene trapped(82)
Interactions
Etf1 interacts with 409 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, protein methylation, ...
Component cytoplasm
Function poly(A) RNA binding, translation release factor activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (41)    Tissues (27)    Images (13)
Theiler Stages: 19, 23, 28
Assay TypeResults
RNA in situ 41
cDNA source data(242)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(242) cDNA(242)
Microarray probesets(12)
Other database
links
VEGA Gene ModelOTTMUSG00000042433 (Evidence)
Ensembl Gene ModelENSMUSG00000024360 (Evidence)
Entrez Gene225363 (Evidence)
UniGene329353
DFCITC1573573, TC1612983, TC1744086
DoTSDT.101391486, DT.101738066, DT.532522, DT.55128998, DT.91335431
NIA Mouse Gene IndexU038315
Consensus CDS ProjectCCDS29137.1
International Mouse Knockout Project StatusEtf1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000042433 VEGA Gene Model | MGI Sequence Detail 29223 C57BL/6J ±  kb
transcript OTTMUST00000111915 VEGA | MGI Sequence Detail 3709 Not Applicable 
polypeptide OTTMUSP00000062763 VEGA | MGI Sequence Detail 437 Not Applicable 

For the selected sequences
All sequences(65) RefSeq(6) UniProt(7)
Polymorphisms SNPs within 2kb(122 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005140 eRF1 domain 1/Pelota-like
InterPro IPR005141 eRF1 domain 2
InterPro IPR005142 eRF1 domain 3
InterPro IPR004403 Peptide chain release factor eRF1/aRF1
InterPro IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal
Protein Ontology PR:000007214 eukaryotic peptide chain release factor subunit 1
References (Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(43)
Other
accession IDs
MGI:2147237

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory