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Etf1 Gene Detail
Summary
  • Symbol
    Etf1
  • Name
    eukaryotic translation termination factor 1
  • Synonyms
    ERF1, MGC:18745, SUP45L1, TB3-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385071
    NCBI Gene: 225363
  • Gene Overview
    MyGene.info: ETF1
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:34902785-34932003 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 18.78 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    121 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385071
protein coding gene Chr18:34902785-34932007 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024254
protein coding gene Chr18:33148905-33181166 (-)
A/J MGP_AJ_G0024220
protein coding gene Chr18:32021241-32051597 (-)
AKR/J MGP_AKRJ_G0024188
protein coding gene Chr18:32941831-32972381 (-)
BALB/cJ MGP_BALBcJ_G0024220
protein coding gene Chr18:32078362-32107615 (-)
C3H/HeJ MGP_C3HHeJ_G0023987
protein coding gene Chr18:32955818-32987521 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024662
protein coding gene Chr18:34410123-34439433 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022102
protein coding gene Chr18:32161379-32190395 (-)
CAST/EiJ MGP_CASTEiJ_G0023462
protein coding gene Chr18:32925463-32955653 (-)
CBA/J MGP_CBAJ_G0023955
protein coding gene Chr18:35364777-35395625 (-)
DBA/2J MGP_DBA2J_G0024087
protein coding gene Chr18:31675463-31704890 (-)
FVB/NJ MGP_FVBNJ_G0024054
protein coding gene Chr18:31360915-31390427 (-)
LP/J MGP_LPJ_G0024169
protein coding gene Chr18:33230915-33263988 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024082
protein coding gene Chr18:36610432-36640758 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024710
protein coding gene Chr18:32766276-32796161 (-)
PWK/PhJ MGP_PWKPhJ_G0023206
protein coding gene Chr18:31885193-31915128 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023014
protein coding gene Chr18:33039684-33067085 (-)
WSB/EiJ MGP_WSBEiJ_G0023525
protein coding gene Chr18:32696206-32725377 (-)



Homology
more
  • Human Ortholog
    ETF1, eukaryotic translation termination factor 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ETF1, eukaryotic translation termination factor 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    D5S1995, ERF, ERF1, RF1, SUP45L1, TB3-1
  • Links
    NCBI Gene ID: 2107
    neXtProt AC: NX_P62495
    UniProt: P62495

  • Chr Location
    5q31.2; chr5:138506093-138543300 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 225363 NCBI Gene Model | MGI Sequence Detail 29219 C57BL/6J ±  kb
transcript NM_144866 RefSeq | MGI Sequence Detail 3718 C57BL/6  
polypeptide Q8BWY3 UniProt | EBI | MGI Sequence Detail 437 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 243
    cDNA 243

    Microarray probesets 12
Other
Accession IDs
less
MGI:2147237
References
more
  • Summaries
    All 39
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 10
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:255082 Kurogi S, et al., Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models. Sci Rep. 2017 Jan 20;7:40692

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory