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Pex6
Gene Detail
Symbol

Name
ID
Pex6
peroxisomal biogenesis factor 6
MGI:2385054
Synonyms
D130055I09Rik, MGC:6455
Feature Type
protein coding gene
Genetic Map
Chromosome 17
22.90 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr17:46711463-46725541 bp, + strand
From VEGA annotation of GRCm38

  14079 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:47914  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Pex6

Human
homologs
Human Homolog PEX6, peroxisomal biogenesis factor 6
NCBI Gene ID 5190
neXtProt AC  NX_Q13608
Human Synonyms  PAF2, PAF-2, PBD4A, PDB4B, PXAAA1
Human Chr (Location)  6p21.1; chr6:42963873-42979243 (-)  GRCh38
Disease Associations  (2) Diseases Associated with Human PEX6
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Pex6 interacts with 40 markers (Mir30c-1, Mir30c-2, Mir34b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process ATP catabolic process, peroxisome organization, ...
Component cytoplasm, cytosol, ...
Function ATPase activity, ATPase activity, coupled, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (7)    Tissues (7)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 7
cDNA source data(9)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(10) cDNA(9) Primer pair(1)
Microarray probesets(8)
Other database
links
VEGA Gene ModelOTTMUSG00000026320 (Evidence)
Ensembl Gene ModelENSMUSG00000002763 (Evidence)
Entrez Gene224824 (Evidence)
DFCITC1589644, TC1576029, TC1595999, TC1602676, TC1658226
DoTSDT.101361267, DT.101266910, DT.492069, DT.97409425, DT.91560082, DT.94404680
NIA Mouse Gene IndexU151276
Consensus CDS ProjectCCDS28837.1
International Mouse Knockout Project StatusPex6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026320 VEGA Gene Model | MGI Sequence Detail 14079 C57BL/6J ±  kb
transcript OTTMUST00000065100 VEGA | MGI Sequence Detail 3200 Not Applicable 
polypeptide OTTMUSP00000032402 VEGA | MGI Sequence Detail 981 Not Applicable 

For the selected sequences
All sequences(55) RefSeq(2) UniProt(5)
Polymorphisms
SNPs within 2kb(77 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003593 AAA+ ATPase domain
InterPro IPR003960 ATPase, AAA-type, conserved site
InterPro IPR003959 ATPase, AAA-type, core
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000012567 peroxisome assembly factor 2
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)
Other
accession IDs
MGI:2146801, MGI:2445130

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory