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Alg12
Gene Detail
Symbol

Name
ID
Alg12
asparagine-linked glycosylation 12 (alpha-1,6-mannosyltransferase)
MGI:2385025
Synonyms
ECM39, mannosyltransferase, MGC:29374
Feature Type
protein coding gene
Genetic Map
Chromosome 15
44.30 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr15:88805244-88819318 bp, - strand
From VEGA annotation of GRCm38

  14075 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:36269  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Alg12

Human
homologs
Human Homolog ALG12, ALG12, alpha-1,6-mannosyltransferase
NCBI Gene ID 79087
neXtProt AC  NX_Q9BV10
Human Synonyms  CDG1G, ECM39, hALG12, PP14673
Human Chr (Location)  22q13.33; chr22:49903204-49918458 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human ALG12
Mutations,
alleles, and
phenotypes
All mutations/alleles(20) : Gene trapped(16) Radiation induced(1) Targeted(3)
Genomic Mutations involving Alg12 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Alg12 interacts with 85 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(22)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(22) cDNA(22)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000031154 (Evidence)
Ensembl Gene ModelENSMUSG00000035845 (Evidence)
Entrez Gene223774 (Evidence)
UniGene41512
DFCITC1584549, TC1589388
DoTSDT.101365428, DT.527780
NIA Mouse Gene IndexU036514
EC2.4.1.260
Consensus CDS ProjectCCDS27732.1, CCDS49694.1
International Mouse Knockout Project StatusAlg12
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031154 VEGA Gene Model | MGI Sequence Detail 14075 C57BL/6J ±  kb
transcript OTTMUST00000077174 VEGA | MGI Sequence Detail 2130 Not Applicable 
polypeptide OTTMUSP00000040753 VEGA | MGI Sequence Detail 486 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(6) UniProt(5)
Polymorphisms
SNPs within 2kb(34 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005599 GPI mannosyltransferase
Protein Ontology PR:000003940 dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase
References
(Earliest) J:77825 Chantret I, et al., Congenital disorders of glycosylation type Ig is defined by a deficiency in dolichyl-P-mannose:Man7GlcNAc2-PP-dolichyl mannosyltransferase. J Biol Chem. 2002 Jul 12;277(28):25815-22
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory