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Nrbp2 Gene Detail
Summary
  • Symbol
    Nrbp2
  • Name
    nuclear receptor binding protein 2
  • Synonyms
    MGC:12117, MGC:18994
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385017
    NCBI Gene: 223649
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:75957367-75963476 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 35.35 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    170 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385017
 protein coding gene Chr15:75957364-75963539 (-)
129S1/SvImJ ENSMUSG00200049773
 protein coding gene Chr15:73074628-73080737 (-)
A/J ENSMUSG00195047706
 protein coding gene Chr15:73049053-73055162 (-)
AKR/J ENSMUSG00220048465
 protein coding gene Chr15:73060107-73066218 (-)
BALB/cJ ENSMUSG00180049678
 protein coding gene Chr15:72875772-72881883 (-)
C3H/HeJ ENSMUSG00175048293
 protein coding gene Chr15:73237651-73243760 (-)
C57BL/6NJ ENSMUSG00215051346
 protein coding gene Chr15:72966451-72972560 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019911
 protein coding gene Chr15:70037802-70042208 (-)
CAST/EiJ ENSTCUG00005038771
 protein coding gene Chr15:72584717-72590848 (-)
CBA/J ENSMUSG00210046902
 protein coding gene Chr15:73012891-73019000 (-)
DBA/2J ENSMUSG00185043223
 protein coding gene Chr15:72991611-72997720 (-)
FVB/NJ ENSMUSG00205029558
 protein coding gene Chr15:72742325-72748434 (-)
JF1/MsJ ENSUMUG00000055472
 protein coding gene Chr15:72650581-72656691 (-)
LP/J ENSMUSG00230051540
 protein coding gene Chr15:76355577-76361686 (-)
NOD/ShiLtJ ENSMUSG00190038567
 protein coding gene Chr15:72995305-73001418 (-)
NZO/HlLtJ ENSMUSG00225049449
 protein coding gene Chr15:76660098-76666207 (-)
PWK/PhJ ENSLUMG00010048292
 protein coding gene Chr15:72931689-72937802 (-)
SPRET/EiJ ENSMSPG00010048499
 protein coding gene Chr15:74543830-74549932 (-)
WSB/EiJ ENSIUOG00005044039
 protein coding gene Chr15:73052377-73058492 (-)



Homology
more
  • Human Ortholog
    NRBP2, nuclear receptor binding protein 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NRBP2, nuclear receptor binding protein 2
  • Synonyms
    pp9320, TRG16
  • Links
    NCBI Gene ID: 340371
    UniProt: Q9NSY0

  • Chr Location
    8q24.3; chr8:143829776-143840973 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    34 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    677
  • Tissues
    54
  • cDNA Data
    62
  • Literature Summary
    5
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000075590 Ensembl Gene Model | MGI Sequence Detail 6110 C57BL/6J ±  kb
transcript ENSMUST00000228366 Ensembl | MGI Sequence Detail 3192 Not Applicable  
polypeptide ENSMUSP00000154287 Ensembl | MGI Sequence Detail 499 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000011419 nuclear receptor-binding protein 2
    (term hierarchy)
  • InterPro Domains
    IPR042697 Nuclear receptor-binding protein 2, pseudokinase domain
    IPR000719 Protein kinase domain
    IPR011009 Protein kinase-like domain superfamily
    IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domain
    IPR050588 With No Lysine (K) Ser/Thr Protein Kinase
  • GlyGen
    Q91V36 1 site
Molecular
Reagents
less
  • All nucleic 62
    cDNA 62
    Antibodies 1

    Microarray probesets 4
References
more
  • Summaries
    All 64
    Developmental Gene Expression 5
    Diseases 1
    Gene Ontology 5
    Phenotypes 34
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory