About   Help   FAQ
Lrrc3b Gene Detail
Summary
  • Symbol
    Lrrc3b
  • Name
    leucine rich repeat containing 3B
  • Synonyms
    LRP15
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384996
    NCBI Gene: 218763
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:15357515-15438987 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 7.08 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1079 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384996
protein coding gene Chr14:15357515-15438987 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021013
protein coding gene Chr14:7962039-8047976 (-)
A/J MGP_AJ_G0020961
protein coding gene Chr14:7723263-7807913 (-)
AKR/J MGP_AKRJ_G0020938
protein coding gene Chr14:7910993-7993905 (-)
BALB/cJ MGP_BALBcJ_G0020964
protein coding gene Chr14:7756680-7838405 (-)
C3H/HeJ MGP_C3HHeJ_G0020748
protein coding gene Chr14:8026547-8109039 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021397
protein coding gene Chr14:8188369-8290216 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018966
protein coding gene Chr14:8358107-8438686 (-)
CAST/EiJ MGP_CASTEiJ_G0020271
protein coding gene Chr14:7918521-7998693 (-)
CBA/J MGP_CBAJ_G0020714
protein coding gene Chr14:8535837-8627807 (-)
DBA/2J MGP_DBA2J_G0020838
protein coding gene Chr14:7660153-7741941 (-)
FVB/NJ MGP_FVBNJ_G0020820
protein coding gene Chr14:7545839-7628626 (-)
LP/J MGP_LPJ_G0020913
protein coding gene Chr14:7992529-8079215 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020846
protein coding gene Chr14:8488055-8568711 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021430
protein coding gene Chr14:7798303-7885480 (-)
PWK/PhJ MGP_PWKPhJ_G0020022
protein coding gene Chr14:7694097-7777499 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019842
protein coding gene Chr14:8001199-8082540 (-)
WSB/EiJ MGP_WSBEiJ_G0020328
protein coding gene Chr14:7878878-7966037 (-)



Homology
more
  • Human Ortholog
    LRRC3B, leucine rich repeat containing 3B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    LRRC3B, leucine rich repeat containing 3B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    LRP15
  • Links
    NCBI Gene ID: 116135
    neXtProt AC: NX_Q96PB8
    UniProt: Q96PB8

  • Chr Location
    3p24.1; chr3:26622806-26717301 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 14190
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: LRRC3B
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    3 phenotype references
Mice homozygous for a knock-out allele exhibit normal olfactory epithelium and bulb.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 218763 NCBI Gene Model | MGI Sequence Detail 81473 C57BL/6J ±  kb
transcript NM_146052 RefSeq | MGI Sequence Detail 1676 C57BL/6  
polypeptide Q8VCH9 UniProt | EBI | MGI Sequence Detail 259 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 3
References
more
  • Summaries
    All 25
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:144660 Yoshida Y, et al., PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord. Neuron. 2006 Dec 7;52(5):775-88
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/03/2019
MGI 6.14
The Jackson Laboratory