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Wrap53
Gene Detail
 Symbol
Name
ID
Wrap53
WD repeat containing, antisense to Trp53
MGI:2384933
Synonyms MGC:28622, Wdr79
Feature Type protein coding gene
Genetic Map
Chromosome 11
42.81 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:69561758-69580255 bp, - strand
From VEGA annotation of GRCm38

  18498 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9995  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Gene Tree: Wrap53

Human
homologs
Human Homolog WRAP53, WD repeat containing, antisense to TP53
NCBI Gene ID 55135
neXtProt AC  NX_Q9BUR4
Human Synonyms  DKCB3, TCAB1, WDR79
Human Chr (Location)  17p13.1; chr17:7686071-7703502 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human WRAP53
Mutations,
alleles, and
phenotypes
All mutations/alleles(24) : Gene trapped(22) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process positive regulation of telomerase activity, telomere formation via telomerase
Component Cajal body, cytoplasm, ...
Function RNA binding
External Resources: FuncBase
Expression
cDNA source data(35)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(35) cDNA(35)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000005983 (Evidence)
Ensembl Gene ModelENSMUSG00000041346 (Evidence)
Entrez Gene216853 (Evidence)
UniGene31586
DFCITC1576900, TC1694136
DoTSDT.101203445, DT.40138578, DT.94193579, DT.97414635
NIA Mouse Gene IndexU032966
Consensus CDS ProjectCCDS24897.1
International Mouse Knockout Project StatusWrap53
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005983 VEGA Gene Model | MGI Sequence Detail 18498 C57BL/6J ±  kb
transcript OTTMUST00000013383 VEGA | MGI Sequence Detail 1891 Not Applicable 
polypeptide OTTMUSP00000006196 VEGA | MGI Sequence Detail 532 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(7) UniProt(2)
Polymorphisms SNPs within 2kb(192 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001680 WD40 repeat
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000017399 telomerase Cajal body protein 1
References (Earliest) J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory